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Visualitzant per matèria "Hormonas"

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    • ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling 

      Wright, Roni; LeDily, Francois; Soronellas, Daniel; Pohl, Andy; Bonet, Jaume; Nacht, A. S.; Vicent, Guillermo Pablo; Wierer, Michael; Oliva, Baldomero; Beato, Miguel (Science, 2016)
      Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ATP ...

    • Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex 

      Mir, Joan Francesc; Zagmutt, Sebastián; Lichtenstein, Mathieu P.; García-Villoria, Judit; Weber, Minéia; Gracia, Ana; Fabriàs, Gemma; Casas, Josefina; López, Miguel; Casals i Farré, Núria; Ribes, Antònia; Suñol, Cristina; Herrero Rodríguez, Laura; Serra, Dolors (Springer Nature, 2018)
      Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...

    • Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters 

      Nacht, Ana Silvina; Pohl, Andy; Zaurín Quer, Roser; Soronellas, Daniel; Quilez, Javier; Sharma, Priyanka; Wright, Roni; Beato, Miguel; Vincent, Guillermo P. (The EMBO Journal, 2016)
      Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is ...