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    • ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling 

      Wright, Roni; LeDily, Francois; Soronellas, Daniel; Pohl, Andy; Bonet, Jaume; Nacht, A. S.; Vicent, Guillermo Pablo; Wierer, Michael; Oliva, Baldomero; Beato, Miguel (Science, 2016)
      Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ATP ...

    • EvolClustDB: exploring eukaryotic gene clusters with evolutionarily conserved genomic neighbourhoods 

      Marcet-Houben, Marina; Collado Cala, Ismael; Fuentes Palacios, Diego; Gómez, Alicia D.; Molina, Manuel; Garisoain, Andrés; Chorostecki, Uciel Pablo; Gabaldón, Toni (Journal of Molecular Biology, 2023)
      Conservation of gene neighbourhood over evolutionary distances is generally indicative of shared regulation or functional association among genes. This concept has been broadly exploited in prokaryotes ...