Visualitzant per matèria "Breast cancer"
Ara mostrant els elements 1-18 de 18
-
90 years of progesterone: molecular mechanisms of progesterone receptor action on the breast cancer genome
(Journal of Molecular Endocrinology, 2020)Gene regulation by steroid hormones has been at the forefront in elucidating the intricacies of transcriptional regulation in eukaryotes ever since the discovery by Karlson and Clever that the insect ... -
Breast cancer-related lymphoedema: risk factors and prediction model
(Journal of Advanced Nursing, 2021)Aims: To identify the risk factors for lymphoedema following axillary lymph node dissection (ALND) in a European sample and to propose a lymphoedema prediction model for this population. Design: Predictive ... -
CDKN1A/p21 in breast cancer: part of the problem, or part of the solution?
(International Journal of Molecular Sciences, 2023)Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ... -
Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy
(npj Breast Cancer, 2024)In this study, we performed genomic analyses of cell cycle and tumor microenvironment changes during and after ribociclib and letrozole or chemotherapy in the CORALLEEN trial. 106 women with untreated ... -
Correlation between superficial and deep lymphatic systems using magnetic resonance lymphangiography in breast cancer-related lymphedema: clinical implications
(Journal of Plastic, Reconstructive & Aesthetic Surgery, 2020)Background: Magnetic resonance lymphangiography (MRL) has increased our knowledge of lymphatic anatomy and lymphedema pathophysiology and improved the efficacy of microsurgical procedures to manage ... -
Cpt1c downregulation causes plasma membrane remodelling and anthracycline resistance in breast cancer
(International Journal of Molecular Sciences, 2023)Breast cancer (BC) is the most common malignancy in women worldwide. While the main systemic treatment option is anthracycline-containing chemotherapy, chemoresistance continues to be an obstacle to ... -
Edad y repercusiones psicológicas en supervivientes de cáncer de mama: revisión sistemática de la literatura
(2025)El cáncer de mama, además de su impacto físico, puede generar secuelas psicológicas persistentes, incluso tras la remisión. Desde una perspectiva teórica, la supervivencia al cáncer ya no se concibe ... -
Estimación del riesgo de cáncer de pulmón en mujeres que participan en un programa de cribado poblacional de cáncer de mama
(Archivos de Bronconeumología, 2020)Introducción: La mortalidad por cáncer de pulmón está aumentando en mujeres. Se ha proyectado que en España pueda superar a la mortalidad por cáncer de mama, la principal causa de mortalidad por cáncer ... -
Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
(Frontiers in Endocrinology, 2022)Background: Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that ... -
Hidden costs in breast cancer-related lymphedema
(Elsevier, 2021)Breast cancer is the most common neoplastic process in women, with an incidence of 2,088,849 cases in 2018, and an overall 5-year survival of 90% and a 10-year survival of 83%.1 Lymphedema secondary to ... -
Hormone-control regions mediate steroid receptor–dependent genome organization
(Genome Research, 2019)In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ... -
Immediate lymphatic reconstruction with targeted lymphatic axillary repair
(Journal of Plastic, Reconstructive & Aesthetic Surgery, 2025)Current surgical treatment for established lymphedema can be challenging and not always successful. To reduce the incidence of post-operative lymphedema, we began trialing targeted lymphatic axillary ... -
Multidisciplinary preventive intervention for breast cancer-related lymphedema: an international consensus
(European Journal of Cancer Care, 2022)Objective: To establish a consensus regarding the multidisciplinary prevention of breast cancer-related lymphedema (BCRL), taking into account the expert opinion of professional groups from across the ... -
Prospective study of shoulder strength, shoulder range of motion, and lymphedema in breast cancer patients from pre-surgery to 5 years after ALND or SLNB
(Supportive Care in Cancer, 2018)Objective: Determine the changes in shoulder strength, shoulder range of motion, and arm volume in breast cancer patients treated with sentinel lymph node biopsy (SLNB) or axillary lymph node dissection ... -
Role of CPT1C in breast cancer development and chemoresistance
(Data de defensa: 2021-07-14)Carnitine palmitoyl transferase 1 (CPT1) are enzymes that catalyze the conversion of long-chain acyl-CoA to acyl-carnitines, to transport long-chain fatty acids across intracellular membranes. CPT1C ... -
Signalling network of breast cancer cells in response to progesterone
(BioRxiv, 2020)Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that transmit ... -
Temporal validation of a risk prediction model for breast cancer-related lymphoedema in European population: a retrospective study
(Journal of Advanced Nursing, 2023)Aims: To perform temporal validation of a risk prediction model for breast cancer-related lymphoedema in the European population. Design: Temporal validation of a previously developed prediction model ... -
Unliganded progesterone receptor governs estrogen receptor gene expression by regulating DNA methylation in breast cancer cells
(Cancers, 2018)Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ...