Biofunctional polyethylene glycol coatings on titanium: an in vitro-based comparison of functionalization methods

Three methods for the production of Polyethylene glycol (PEG) coatings on titanium are compared, i.e. plasma polymerization, electrodeposition and silanization. The compared deposition methods presented similar wettability (hydrophilic coatings), chemical composition assessed by XPS and thickness around 1 nm. The coatings lowered albumin adsorption and presented a decreased fibroblast, Streptococcus sanguinis and Lactobacillus salivarius adhesion. Immobilization of a cell adhesion peptide (RGD) presented a higher fibroblast adhesion and no alteration of the bacterial adhesion, giving three methods for the biofunctionalization of titanium for dental implants. The feasibility of each methodology is compared in terms of the process parameters in order to provide a guide for the election of the methodology.

Document Type

Article

Document version

Accepted version

Language

English

Subject (CDU)

616.3 - Pathology of the digestive system. Complaints of the alimentary canal

Keywords

Polietilenglicol

Implants de titani

Biofuncionalització

Polimerització per plasma

Polimerización por plasma

Bio functionalization

Plasma polymerization

Silanization

Electrodeposition

Publisher

Elsevier

Collection

152;

Is part of

Colloids and Surfaces B. Biointerfaces

Recommended citation

Buxadera Palomero, Judit; Calvo Muñoz, Cristina; Torrent Camarero, Sergi [et al.]. Biofunctional polyethylene glycol coatings on titanium: an in vitro-based comparison of functionalization methods. Colloids and Surfaces B. Biointerfaces, 2017, 152, p. 367-375. Disponible en: <https://www.sciencedirect.com/science/article/abs/pii/S0927776517300619>. Fecha de acceso: 12 nov. 2021. DOI: 10.1016/j.colsurfb.2017.01.042

Grant agreement number

info:eu-repo/grantAgreement/ES/MINECO/MAT2015-67183-R

Note

The authors acknowledge financial support of Technical University of Catalonia and Fundación Ramón Areces through the fellowship of JB-P. Financial support for the project is acknowledged to Fundación Ramón Areces through project “Biosellado”, the Spanish Government through Ramon y Cajal fellowships of CC and CM-M, and project MAT2015-67183-R, co-funded by the EU through European Regional Development Funds, and the European Cooperation in Science and Technology, COST action MP1101. The authors also wish to express their gratitude to Montserrat Domínguez, for her useful comments and advice regarding the XPS analysis.

Show full item record

This item appears in the following Collection(s)

Odontologia [345]