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Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex
(Experimental and molecular medicine, 2019)
CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that forms an active complex with cyclin Y (CCNY). Although both proteins have been recently ...
Lower admission blood pressure as an independent predictor of 1-year mortality in elderly patients experiencing a first hospitalization for acute heart failure
(Elsevier, 2019)
Background: Systolic blood pressure (SBP) is an acknowledged prognostic factor in patients with heart failure (HF). Admission SBP should be a risk factor for 1-year mortality even in elderly patients ...
Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1
(eLife Sciences Publications, 2019-09-13)
Loss of proteostasis and cellular senescence are key hallmarks of aging, but direct
cause-effect relationships are not well understood. We show that most yeast cells arrest in G1
before death with low ...
Osteo-odonto-, tibial bone and Boston keratoprosthesis in clinically comparable cases of chemical injury and autoimmune disease
(Elsevier, 2019)
Purpose: To compare anatomical and functional results between three types of keratoprosthesis (KPro) in chemical injury and autoimmune disease. Methods: 70 clinically comparable cases were included as ...
Targeting DNA repair defects for precision medicine in prostate cancer
(Springer Nature, 2019)
Purpose of Review: Genomic studies of localized and metastatic prostate cancer have identified a high prevalence of clinically actionable alterations including mutations in DNA repair genes. In this ...
Cost minimization analysis for basic life support
(Elsevier, 2019)
Background: The use of online teaching methodology for basic life support (BLS) courses is progressively increasing. Objective: The objective of this study was to verify whether the blended-learning ...
Histological comparison of in vitro and in vivo development of peripheral posterior capsule opacification in human donor tissue
(Elsevier, 2019)
In order to study the mechanisms involved in the development of posterior capsule opacification (PCO) we compared in vivo developed PCO with PCO formed in tissue culture with focus on the periphery of ...
Combined aerobic exercise and high-intensity respiratory muscle training in patients surgically treated for non-small cell lung cancer: a pilot randomized clinical trial
(Edizioni Minerva Medica, 2019)
BACKGROUND: Lung resection surgery further decreases exercise capacity and negatively affects respiratory muscle function in patients with non-small cell lung cancer (NSCLC). The best design for exercise ...
The effectiveness of extracorporeal shock wave therapy to reduce lower limb spasticity in stroke patients: a systematic review and meta-analysis
(Taylor & Francis, 2019)
Objective: To assess the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) to reduce lower limb spasticity in adult stroke survivors. Data Sources: A systematic review of Medline/Pubmed, CENTRAL, ...
Advantages and disadvantages of implant navigation surgery. A systematic review
(Elsevier, 2019)
This review elucidates the advantages and disadvantages of the different implant navigation methods to assist the precise surgical placement of dental implants. Implant navigation surgery can be classified ...