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Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): surveillance data from 23 sites in Catalonia, Spain
(Public Library of Science, 2020-02)
Background: The objective of this study is to describe incidence and shifts of serotype and clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups (<5 years, 5–17 ...
Limited joint mobility progression in type 1 diabetes: a 15-year follow-up study
(Hindawi Limited, 2018)
Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different ...
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
(Springer Nature, 2020-09-10)
Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...
Biofabrication of collagen tissue-engineered blood vessels with direct co-axial extrusion
(MDPI, 2022)
Cardiovascular diseases are considered one of the worldwide causes of death, with atherosclerosis being the most predominant. Nowadays, the gold standard treatment is blood vessel replacement by bypass ...
Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle
(American Society for Biochemistry and Molecular Biology, 1994-04-22)
The isoprenoid pathway leads to various essential non-sterol products in insects. These end products have a crucial role in growth, differentiation, sexual maturation, and reproduction. 3-Hydroxy-3-me ...
Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: a promising strategy to regulate energy balance
(John Wiley & Sons, 2023)
Tackling the growing incidence and prevalence of obesity urgently requires uncovering new molecular pathways with therapeutic potential. The brain, and in particular the hypothalamus, is a major integrator ...
Impact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental study
(Frontiers Media, 2020-04-02)
The aim of the study was to evaluate the impact of a multifaceted antimicrobial stewardship intervention on antibiotic consumption in a primary health care (PHC) area in Spain. Quasi-experimental study ...
Competencies in basic life support after a course with or without rescue ventilation: historical cohort study
(MDPI, 2022)
Background: Simplifying the international guidelines to improve skills after training and their retention over time has been one of the top priorities in recent years. The objective of our study was to ...
Estado de salud de personas inmigrantes en Cataluña desde una perspectiva de género: Proyecto PELFI
(Elsevier, 2022)
Objetivo: Evaluar el estado de salud de hombres y mujeres inmigrantes extracomunitarios residentes en el Área Metropolitana de Barcelona (Cataluña, España) e identificar determinantes sociales de la ...
Effect of an unsupervised exercises-based athletics injury prevention programme on injury complaints leading to participation restriction in athletics: a cluster-randomised controlled trial
(MDPI, 2021)
Objective: To test the efficacy of the Athletics Injury Prevention Programme (AIPP) to reduce the percentage of athletes presenting at least one injury complaint leading to participation restriction ...