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Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders
(Dove Press, 2011-03-28)
Acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) are two naturally occurring carnitine derivates formed by carnitine acetyltransferase. The beneficial cardiovascular effects of ALC and PLC have ...
The effect of oral citicoline and docosahexaenoic acid on the visual field of patients with glaucoma: a randomized trial
(MDPI, 2022)
The role of nutraceuticals in the treatment of glaucoma remains controversial. The aim of this study was to evaluate the effect of citicoline, vitamin C, and docosahexaenoic acid (DHA) in patients with ...
Does the addition of manual therapy approach to a cervical exercise program improve clinical outcomes for patients with chronic neck pain in short -and mid-term? A randomized controlled trial
(MDPI, 2020)
Chronic neck pain is one of today’s most prevalent pathologies. The International Classification of Diseases categorizes four subgroups based on patients’ associated symptoms. However, this classification ...
The use of next-generation sequencing in the diagnosis of rare inherited anaemias: a joint BSH/EHA good practice paper
(John Wiley & Sons, 2022)
The British Society for Haematology (BSH) produces Good Practice Papers to recommend good practice in areas where there is a limited evidence base but for which a degree of consensus or uniformity is ...
Asymptomatic carotid atherosclerosis cardiovascular risk factors and common hypertriglyceridemia genetic variants in patients with systemic erythematosus lupus
(MDPI, 2021)
SLE is associated with increased cardiovascular risk. The objective of this study was to determine the prevalence of asymptomatic carotid atherosclerosis to analyze its relationship with dyslipidemia ...
Genetic and clinical heterogeneity in thirteen new cases with aceruloplasminemia. Atypical anemia as a clue for an early diagnosis
(MDPI, 2020)
Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation ...
Impaired cerebral autoregulation is associated with brain dysfunction in patients with sepsis
(Springer Nature, 2018-12-04)
Background: Sepsis-associated brain dysfunction (SABD) is associated with high morbidity and mortality. The pathophysiology of SABD is multifactorial. One hypothesis is that impaired cerebral autoregulation ...
Análisis de la evolución en el acceso a los medicamentos huérfanos en España
(Elsevier, 2020)
Objetivo: Evaluar el acceso al mercado de los medicamentos huérfanos en España que a fecha de 31 de diciembre de 2017 tuvieran vigente su designación, y para aquellos comercializados en España estimar ...
How did the COVID-19 lockdown affect children and adolescent's well-being: spanish parents, children, and adolescents respond
(Frontiers Media, 2021)
Background: During the COVID-19 pandemic, lockdown strategies have been widely used to contain SARS-CoV-2 virus spread. Children and adolescents are especially vulnerable to suffering psychological ...
Injuries of the subscapularis: prevalence of partial lesions and their diagnostic difficulty
(Fundación Española de Artroscopia, 2021-12)
Objective: to conduct a review of partial ruptures of the subscapularis muscle (SSC) and establish their prevalence and preoperative diagnostic difficulty, as well as their frequent association to ...