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Now showing items 11-20 of 222
A nucleotide-based drug protects against glutamate- and MPP+ -induced neurotoxicity
(Scientific Research, 2011)
Nucleo CMP Forte® is a nucleotide-based drug consisting of cytidinemonophosphate, uridinemonophosphate, uridin-ediphosphate and uridinetriphosphate. It has been prescribed for peripheral nervous system ...
Sarampión en Europa: necesidad de acción global y local para su erradicación
(Elsevier, 2018)
Uno de los objetivos actuales de la Organización Mundial de la Salud (OMS) es la erradicación del sarampión y la rubéola en al menos cinco regiones de la OMS para el año 2020, como se recoge en el Plan ...
Two opposing faces of retinoic acid: induction of stemness or induction of differentiation depending on cell-type
(MDPI, 2019)
Stem cells have the capacity of self-renewal and, through proliferation and differentiation, are responsible for the embryonic development, postnatal development, and the regeneration of tissues in the ...
Eradication of hepatitis C virus and non-liver-related non–acquired immune deficiency syndrome–related events in human immunodeficiency virus/hepatitis C virus coinfection
(John Wiley & Sons, Inc., 2017)
We assessed non-liver-related non–acquired immunodeficiency syndrome (AIDS)-related (NLR-NAR) events and mortalityin a cohort of human immunodeficiency virus (HIV)/hepatitis C virus (HCV)–coinfected ...
High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial
(Springer Nature, 2017-05-02)
Background: Extubation failure is associated with increased morbidity and mortality, but cannot be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation respiratory failure ...
Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
(MDPI, 2019)
The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have ...
Mi visita a la enfermería fenomenológica
(Universidad Nacional de Educación a Distancia, 2018)
Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
(Molecular Neurobiology, 2018)
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...
Novel regulation of the synthesis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunit gluA1 by carnitine palmitoyltransferase 1C (CPT1C) in the hippocampus
(American Society for Biochemistry and Molecular Biology, 2015-10-16)
The regulation of AMPA-type receptor (AMPAR) abundance in the postsynaptic membrane is an important mechanism involved in learning and memory formation. Recent data suggest that one of the constituents ...
Scoping review on interventions to improve adherence to reporting guidelines in health research
(BMJ Publishing Group, 2019)
Objectives: The goal of this study is to identify, analyse and classify interventions to improve adherence to reporting guidelines in order to obtain a wide picture of how the problem of enhancing the ...