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CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy
(Nature Research, 2018-05-03)
Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some
applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to
improve ...
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Elsevier, 2019-12)
Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ...
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
(American Society for Biochemistry and Molecular Biology, 2012)
A novel lyase activity enzyme is characterized for the first time: HMG-CoA lyase-like1 (er-cHL), which is a close homolog of mitochondrial HMG-CoA lyase (mHL). Initial data show that there are nine ...
Understanding patients’ experiences of the wish to hasten death: an updated and expanded systematic review and meta-ethnography
(BMJ Publishing Group, 2017)
Objectives: Patients with advanced disease sometimes express a wish to hasten death (WTHD). In 2012, we published a systematic review and meta-ethnography of qualitative studies examining the experience ...
Isolated acute hemorrhagic edema of the eyelids
(ACT Publishing Group Limited, 2019-12)
Perivascular epithelioid cell tumors (PEComas) are rare tumors which can arise in almost every body site. Little is still known about these tumors because of the limited number of cases described by far ...
Hormone-control regions mediate steroid receptor–dependent genome organization
(Cold Spring Harbor Laboratory Press, 2019)
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...
Long-term efficacy and effectiveness of abehavioural and community-basedexercise intervention (Urban Training) toincrease physical activity in patients withCOPD: a randomised controlled trial
(European Respiratory Society, 2018)
There is a need to increase and maintain physical activity in patients with chronic obstructive pulmonary disease (COPD). We assessed 12-month efficacy and effectiveness of the Urban Training intervention ...
Determinants of study completion and response to a 12-month behavioral physical activity intervention in chronic obstructive pulmonary disease: a cohort study
(Public Library of Science, 2019-05-20)
Objectives: Physical activity is key to improve the prognosis of chronic obstructive pulmonary disease (COPD). To help to tailor future interventions we aimed to identify the baseline characteristics ...
Cost-utility and biological underpinnings of Mindfulness-Based Stress Reduction (MBSR) versus a psychoeducational programme (FibroQoL) for fibromyalgia: a 12-month randomised controlled trial (EUDAIMON study)
(Springer Nature, 2016)
Background: The EUDAIMON study focuses on fibromyalgia syndrome (FMS), a prevalent chronic condition characterized by pain, fatigue, cognitive problems and distress. According to recent reviews and ...
Biofunctionalization strategies on tantalum-based materials for osseointegrative applications
(Springer Nature, 2015)
The use of tantalum as biomaterial for orthopedic applications is gaining considerable attention in the clinical practice because it presents an excellent chemical stability, body fluid resistance, ...