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Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
(Molecular Neurobiology, 2018)
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
(Springer Nature, 2023)
Background: Fatty acid metabolism in the hypothalamus has an important role in food intake, but its specific role in AgRP neurons is poorly understood. Here, we examined whether carnitinea palmitoyltransferase ...