Browsing Ciències de la Salut by Title

Now showing items 589-608 of 723

    • Self-learning methodology in simulated environments (MAES©) as a learning tool in perioperative nursing. An evidence-based practice model for acquiring clinical safety competencies 

      Peñataro-Pintado, Ester; Díaz-Agea, José Luis; Castillo, Isabel; Leal-Costa, César; Ramos-Morcillo, Antonio Jesús; Ruzafa-Martínez, María; Rodríguez-Higueras, Encarna (International Journal of Environmental Research and Public Health, 2021)
      Background: The self-learning Methodology in Simulated Environments (Spanish acronym: MAES©, (Murcia, Spain) is a type of self-directed and collaborative training in health sciences. The objective of ...

    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas, Maria; Rut, Fadó; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan, Shigeru; Solé, Montse; Unzeta, Mercedes; Miñano Molina, Alfredo Jesús; Rodríguez-Álvarez, José; James Dickson, Eamonn; Casals i Farré, Núria (Journal of Cell Biology, 2020-09)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...

    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas, Maria; Fadó Andrés, Rut; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan, Shigeru; Solé, Montse; Unzeta, Mercedes; Miñano Molina, Alfredo Jesús; Rodríguez-Álvarez, José; Dickson, Eamonn James; Casals i Farré, Núria (Journal of Cell Biology, 2020)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...

    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas Prat, Maria; Fadó, Rut; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan_, Shigeru; Solé, Montse; UNZETA, Mercedes; Miñano-Molina, Alfredo J; Rodriguez-Alvarez, Jose; Dickson, Eamonn; Casals, Nuria (Journal of Cell Biology, 2020)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...

    • Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth 

      Palomo Guerrero, Marta; Fadó Andrés, Rut; Casas, Maria; Pérez-Montero, Marta; Baena, Miguel; Helmer, Patrick O.; Domínguez, José Luis; Roig, Aina; Serra, Dolors; Hayen, Heiko; Stenmark, Harald; Raiborg, Camilla; Casals i Farré, Núria (eLife, 2019)
      Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty ...

    • Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): surveillance data from 23 sites in Catalonia, Spain 

      Ludwig, Guillermo; Garcia-Garcia, Selene; Lanaspa, Miguel; Ciruela, Pilar; Esteva, Cristina; Fernandez de Sevilla, Mariona; Diaz-Conradi, Alvaro; Marti, Carmina; Motje, Montse; Galles, Carme; Morta, Montse; Izquierdo, Conchita; Moraga-Llop, Fernando; Campins, Magda; Salleras, Luis; Jané, Mireia; Domínguez, Ángela; Garcia-Garcia, Juan Jose; Muñoz-Almagro, Carmen; Catalan Study Group of Invasive Pneumococcal Disease (PLoS One, 2020-02)
      Background: The objective of this study is to describe incidence and shifts of serotype and clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups (<5 years, 5–17 ...

    • Serotype distribution of remaining pneumococcal meningitis in the mature PCV10/13 period: findings from the PSERENADE project 

      Garcia Quesada, Maria; Yang, Yangyupei; Bennett, Julia C.; Hayford, Kyla; Zeger, Scott L.; Feikin, Daniel R.; Peterson, Meagan E.; Cohen, Adam L.; Almeida, Samanta C. G.; Ampofo, Krow; Ang, Michelle; Bar-Zeev, Naor; Bruce, Michael G.; Camilli, Romina; Chanto Chacón, Grettel; Ciruela, Pilar; Cohen, Cheryl; Corcoran, Mary; Dagan, Ron; De Wals, Philippe; Desmet, Stefanie; Diawara, Idrissa; Gierke, Ryan; Guevara, Marcela; Hammitt, Laura L.; Hilty, Markus; Ho, Pak-Leung; Jayasinghe, Sanjay; Kleynhans, Jackie; Kristinsson, Karl G.; Ladhani, Shamez N.; McGeer, Allison; Mwenda, Jason M.; Nuort, J. Pekka; Oishi, Kazunori; Ricketson, Leah J.; Sanz, Juan Carlos; Savrasova, Larisa; Setchanova, Lena Petrova; Smith, Andrew; Valentiner-Branth, Palle; Valenzuela, Maria Teresa; Van der Linden, Mark; Van Sorge, Nina M.; Varon, Emmanuelle; Winje, Brita A.; Yildirim, Inci; Zintgraff, Jonathan; Knoll, Maria Deloria; PSERENADE Team (Microorganisms, 2021)
      Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the ...

    • Serotypes and clonal composition of streptococcus pneumoniae isolates causing IPD in children and adults in Catalonia before 2013 to 2015 and after 2017 to 2019 systematic introduction of PCV13 

      Redin, A.; Ciruela, P.; De Sevilla, M. F.; Gomez-Bertomeu, F.; Gonzalez-Peris, S.; Benitez, M. A.; Trujillo, G.; Diaz, A.; Jou, E.; Izquierdo, C.; Perez-Moreno, M. O.; Moraga-Llop, F.; Olsina, M.; Vinado, B.; Sanfeliu, E.; Garcia, A.; Gonzalez-di Lauro, S.; Garcia-Garcia, J. J.; Dominguez, A.; Sa-Leao, R.; Muñoz Almagro, Carmen; Catalan Study Group of Invasive Pneumococcal DiseaseSHOW FEWER (Microbiology Spectrum, 2021)
      The goal of this study was to investigate the distribution of serotypes and clonal composition of Streptococcus pneumoniae isolates causing invasive pneumococcal disease (IPD) in Catalonia, before and ...

    • Short-term effects of three types of hamstring stretching on length, neurodynamic response, and perceived sense of effort: a randomised cross-over trial 

      López-de-Celis, Carlos; Izquierdo-Nebreda, Pedro; Gonzalez-Rueda, Vanessa; Cadellans-Arróniz, Aïda; Rodríguez-Sanz, Jacobo; Bueno-Gracia, Elena; Albert, Pérez-Bellmunt (Life, 2022)
      Background: Stretching techniques for hamstring muscles have been described both to increase muscle length and to evaluate nerve mechanosensitivity. Aim: We sought to evaluate the short-term effects of ...

    • Signalling network of breast cancer cells in response to progesterone 

      Wright, Roni H.G.; Vastolo, Viviana; Quilez Oliete, Javier; Carbonell-Caballero, José; Beato, Miguel (BioRxiv, 2020)
      Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that transmit ...

    • Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius 

      Godoy Gallardo, Maria; Rodríguez‐Hernández, Ana G.; Delgado, Luis M.; Manero Planella, José María; Gil Mur, Francisco Javier; Rodríguez, Daniel (Clinical Oral Implants Research, 2014-05-30)
      Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ...

    • Simulation methods with extended stability for stiff biochemical Kinetics 

      Rué, Pau; Villà-Freixa, Jordi; Burrage, Kevin (BMC Systems Biology, 2010)
      Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical ...

    • SIREs: searching for iron-responsive elements 

      Campillos, Monica; Cases, Ildefonso; Hentze, Matthias W.; Sanchez, Mayka (Nucleic Acids Research, 2010-07)
      The iron regulatory protein/iron-responsive element regulatory system plays a crucial role in the post-transcriptional regulation of gene expression and its disruption results in human disease. IREs are ...

    • SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2 

      Barroso, Emma; Rodríguez-Rodríguez, Rosalía; Zarei, Mohammad; Pizarro-Delgado, Javier; Planavila, Anna; Palomer, Xavier; Villarroya, Francesc; Vázquez-Carrera, Manuel (Cell Communication and Signaling18;147, 2020-09-10)
      Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...

    • Síndrome de muerte súbita del lactante: ¿siguen las familias las recomendaciones? 

      Ruiz Botia, Irene; Cassanello Peñarroya, Pía; Díez-Izquierdo, Ana; Martínez Sánchez, Jose María; Balaguer Santamaría, Albert (Anales de Pediatría, 2020-04)
      Introducción: La postura en decúbito prono al dormir es el principal factor de riesgo modificable conocido para el síndrome de muerte súbita del lactante (SMSL). Existen otras recomendaciones respecto ...

    • Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts 

      Haggenmüller, Sarah; Maron, Roman C.; Hekler, Achim; Utikal, Jochen S.; Barata, Catarina; Barnhill, Raymond L.; Beltraminelli, Helmut; Berking, Carola; Betz-Stablein, Brigid; Blum, Andreas; Braun, Stephan A.; Carr, Richard; Combalia, Marc; Fernandez Figueras, Maria-Teresa; Ferrara, Gerardo; Fraitag, Sylvie; French, Lars E.; Gellrich, Frank F.; Ghoreschi, Kamran; Goebeler, Matthias; Guitera, Pascale; Haenssle, Holger A.; Haferkamp, Sebastian; Heinzerling, Lucie; Heppt, Markus V.; Hilke, Franz J.; Hobelsberger, Sarah; Krahl, Dieter; Kutzner, Heinz; Lallas, Aimilios; Liopyris, Konstantinos; Llamas-Velasco, Mar; Malvehy, Josep; Meier, Friedegund; Müller, Cornelia S.L.; Navarini, Alexander A.; Navarrete-Dechent, Cristián; Perasole, Antonio; Poch, Gabriela; Podlipnik, Sebastian; Requena, Luis; Rotemberg, Veronica M.; Saggini, Andrea; Sangueza, Omar P.; Santonja, Carlos; Schadendorf, Dirk; Schilling, Bastian; Schlaak, Max; Schlager, Justin G.; Sergon, Mildred; Sondermann, Wiebke; Soyer, H. Peter; Starz, Hans; Stolz, Wilhelm; Vale, Esmeralda; Weyers, Wolfgang; Zink, Alexander; Krieghoff-Henning, Eva I.; Kather, Jakob N.; Von Kalle, Christof; Lipka, Daniel B.; Fröhling, Stefan; Hauschild, Axel; Kittler, Harald; Brinker, Titus J. (European Journal of Cancer, 2021-10)
      Background: Multiple studies have compared the performance of artificial intelligence (AI)–based models for automated skin cancer classification to human experts, thus setting the cornerstone for a ...

    • Smartphone and tablet usage during COVID-19 pandemic confinement in children under 48 months in Barcelona (Spain) 

      Cartanyà-Hueso, Àurea; Lidón Moyano, Cristina; Cassanello Peñarroya, Pía; Díez-Izquierdo, Ana; Martín Sánchez, Juan Carlos; Balaguer Santamaría, Albert; Martínez Sánchez, Jose María (Healthcare, 2021)
      Background: Total lockdown due to COVID-19 pandemic might have potentially increased screen time in children. This study aims to describe the smartphone and tablets usage in children under 48 months ...

    • A social return on investment analysis of improving the management of chronic obstructive pulmonary disease within the spanish national healthcare system 

      Merino, María; Martín Lorenzo, Teresa; Maravilla-Herrera, P.; Ancochea, julio; Gómez Sáenz, JT; Hass, Nicole; MOLINA, JESUS; Peces-Barba, G.; Trapero-Bertran, Marta; trigueros, juan antonio; Hidalgo, Alvaro (International Journal of Chronic Obstructive Pulmonary Disease, 2022)
      Purpose: To define a set of proposals that would improve the current management of chronic obstructive pulmonary disease (COPD) within the Spanish National Healthcare System (SNHS) from a comprehensive ...

    • Socio-economic and psychological impact of COVID-19 pandemic in a Spanish cohort BIOVAL-D-COVID-19 study protocol 

      Miranda-Mendizábal, Andrea; Recoder Fernández, Silvia; Calbo Sebastián, Esther; Casajuana Closas, Marc; Leiva Urena, David; Manolov, Rumen; Matilla-Santander, Nuria; Forero, Carlos G.; Castellví Obiols, Pere (Gaceta Sanitaria, 2021)
      Objective: SARS-CoV-2 outbreak has a negative psychological impact among general population. Data comparing mental health status before and during the outbreak is needed. The BIOVAL-D-COVID-19 study ...

    • Socio-environmental correlates of physical activity in patients with chronic obstructive pulmonary disease (COPD) 

      Arbillaga-Etxarri, Ane; Gimeno-Santos, Elena; Barberan-Garcia, Anael; Benet, Marta; Borrell, Eulàlia; Dadvand, Payam; Foraster, Maria; Marín, Alicia; Monteagudo Zaragoza, Mònica; Rodriguez-Roisin, Robert; Vall Casas, Pere; Vilaró, Jordi; Garcia-Aymerich, Judith; Urban Training Study Group (Thorax, 2017)
      Background. Study of the causes of the reduced levels of physical activity in patients with COPD has been scarce and limited to biological factors. Aim: To assess the relationship between novel ...