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SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
(Springer Nature, 2020-09-10)
Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...
Impact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental study
(Frontiers Media, 2020-04-02)
The aim of the study was to evaluate the impact of a multifaceted antimicrobial stewardship intervention on antibiotic consumption in a primary health care (PHC) area in Spain. Quasi-experimental study ...
Direct health care costs associated to neurological diseases and different degrees of malnutrition
(Elsevier, 2021)
Background and Aims: Home-based care and oral supplemental nutrition may be an efficient way of managing health resources, freeing up hospital resources and improving patient care and quality of life. ...
Effect of an unsupervised exercises-based athletics injury prevention programme on injury complaints leading to participation restriction in athletics: a cluster-randomised controlled trial
(MDPI, 2021)
Objective: To test the efficacy of the Athletics Injury Prevention Programme (AIPP) to reduce the percentage of athletes presenting at least one injury complaint leading to participation restriction ...
Three dimensional porous scaffolds derived from collagen, elastin and fibrin proteins orchestrate adipose tissue regeneration
(Sage Journals, 2021)
Current gold standard to treat soft tissue injuries caused by trauma and pathological condition are autografts and off the shelf fillers, but they have inherent weaknesses like donor site morbidity, ...
Mental well-being of the general population: direct and indirect effects of socioeconomic, relational and health factors
(Springer Nature, 2021)
Purpose: The aim of this study was to analyse the association between individual mental well-being and social, economic, lifestyle and health factors. Methods: Cross-sectional study on a representative ...
Biological roles and delivery strategies for ions to promote osteogenic induction
(Frontiers Media, 2021-01-14)
Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ...
Hereditary hyperferritinemia cataract syndrome: ferritin L gene and physiopathology behind the disease - report of new cases
(MDPI, 2021)
Hereditary hyperferritinemia-cataract syndrome (HHCS) is a rare disease characterized by high serum ferritin levels, congenital bilateral cataracts, and the absence of tissue iron overload. This disorder ...
Accuracy and safety of dry needling placement in the popliteus muscle: a cadaveric study
(John Wiley & Sons, Inc., 2021)
Background: The popliteus muscle attaches posteriorly to the joint capsule of the knee. Although it is an important rotational stabiliser and has been implicated in various knee pathologies, research ...
Clinical significance of indeterminate quantiFERON-TB Gold plus assay results in hospitalized COVID-19 patients with severe hyperinflammatory syndrome
(MDPI, 2021)
Performance of the QuantiFERON-TB Gold Plus (QFT-Plus) assay could be affected by conditions of immune dysregulation. Little is known about the reliability of QTF-Plus in COVID-19 patients. Our aim was ...