Search
Now showing items 1-3 of 3
Dynamic force spectroscopy of DNA hairpins: II. Irreversibility and dissipation
(IOP Publishing, 2009)
We investigate irreversibility and dissipation in single molecules that cooperatively fold/unfold in a two-state manner under the action of mechanical force. We apply path thermodynamics to derive ...
Dynamic force spectroscopy of DNA hairpins: I. Force kinetics and free energy landscapes
(IOP Publishing, 2009)
We investigate the thermodynamics and kinetics of DNA hairpins that fold/unfold under the action of applied mechanical force. We introduce the concept of the molecular free energy landscape and derive ...
Statistical properties of metastable intermediates in DNA unzipping
(American Physical Society, 2009)
We unzip DNA molecules using optical tweezers and determine the sizes of the cooperatively unzipping and zipping regions separating consecutive metastable intermediates along the unzipping pathway. Sizes ...