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Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort
(Elsevier, 2017-06)
Background: The leading high-risk state for diabetes mellitus (DM) – prediabetes – is increasing; however, a lack of information exists in oldest old subjects. The objective of this study is to describe ...
Commentary: Grand challenge: ELSI in a changing global environment
(Frontiers Media, 2017-09-26)
Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning
(Optical Society of America, 2019-02-01)
Glaucoma detection in color fundus images is a challenging task that requires expertise and years of practice. In this study we exploited the application of different Convolutional Neural Networks (CNN) ...
Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): surveillance data from 23 sites in Catalonia, Spain
(Public Library of Science, 2020-02)
Background: The objective of this study is to describe incidence and shifts of serotype and clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups (<5 years, 5–17 ...
Limited joint mobility progression in type 1 diabetes: a 15-year follow-up study
(Hindawi Limited, 2018)
Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different ...
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
(Springer Nature, 2020-09-10)
Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...
Impact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental study
(Frontiers Media, 2020-04-02)
The aim of the study was to evaluate the impact of a multifaceted antimicrobial stewardship intervention on antibiotic consumption in a primary health care (PHC) area in Spain. Quasi-experimental study ...
A nucleotide-based drug protects against glutamate- and MPP+ -induced neurotoxicity
(Scientific Research, 2011)
Nucleo CMP Forte® is a nucleotide-based drug consisting of cytidinemonophosphate, uridinemonophosphate, uridin-ediphosphate and uridinetriphosphate. It has been prescribed for peripheral nervous system ...
Sarampión en Europa: necesidad de acción global y local para su erradicación
(Elsevier, 2018)
Uno de los objetivos actuales de la Organización Mundial de la Salud (OMS) es la erradicación del sarampión y la rubéola en al menos cinco regiones de la OMS para el año 2020, como se recoge en el Plan ...
Two opposing faces of retinoic acid: induction of stemness or induction of differentiation depending on cell-type
(MDPI, 2019)
Stem cells have the capacity of self-renewal and, through proliferation and differentiation, are responsible for the embryonic development, postnatal development, and the regeneration of tissues in the ...