Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort
Author
Padrós, Gloria
Ferrer, Assumpta
Formiga, Francesc
Cunillera, Oriol
Badia, Teresa
Corbella Virós, Xavier
Octabaix Study Group
Publication date
2017-06ISSN
1873-9598
Abstract
Background: The leading high-risk state for diabetes mellitus (DM) – prediabetes – is increasing; however, a lack of information exists in oldest old subjects. The objective of this study is to describe the rate of prediabetes and the associated factors among community-dwelling 85-year-olds. Methods: A cross-sectional survey including data from 321 subjects on cardiovascular risk factors, functional status, comorbidities and laboratory tests was conducted. Participants were divided in three groups: normoglycemic (fasting plasma glucose (FPG) < 5.6 mmol/L), prediabetes (FPG 5.6–6.9 mmol/L) and DM (FPG ≥ 7 mmol/L, or DM diagnostic, or antidiabetics use). Comparative analysis was performed between the 3 groups. Results: One hundred seventy-nine (55.8%) participants were classified as normoglycemic, 86 (26.8%) as DM and 56 (17.4%) as prediabetic. Multinomial logistic regression model found no association of explanatory variables with normoglycemia in front of prediabetes, while there was significant association with DM (rather than prediabetes) and Angiotensin converting enzyme (ACE) treatment (OR: 7.04 95% CI 2.52–19.61), diuretics (OR: 2.46, 95% CI 1.04–5.78) and Charlson Index (OR: 2.67, 95% CI 1.77–4.02), with higher odds of being in DM than in prediabetic group. Conclusion: Prevalence of prediabetes is high among the 85-year-old population studied. The comparison between prediabetic and DM groups revealed that the major clinical differences were the higher Charlson comorbidity Index scores, diuretics and ACE drugs in the DM group.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Diabetis
Gerontologia
Diabetis -- Factors de risc
Diabetes
Gerontología
Diabetes -- Factores de riesgo
Diabetes
Gerontology
Diabetes -- Risk factors
Pages
3
Publisher
Elsevier
Collection
11;
Is part of
International Journal of Gerontology
Citation
Padrós, Gloria; Ferrer, Assumpta; Formiga, Francesc [et al.]. Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort. International Journal of Gerontology, 2017, 11, p. 90-94. Disponible en: <https://www.sciencedirect.com/science/article/pii/S1873959817300637>. Fecha de acceso: 7 jul. 2020. DOI: 10.1016/j.ijge.2016.05.006
This item appears in the following Collection(s)
- Ciències de la Salut [712]
Rights
© 2017 Taiwan Society of Geriatric Emergency & Critical Care Medicine. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/