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The ADP-ribose hydrolase NUDT5 is important for DNA repair
Qi, Hongyun; Wright, Roni; Beato, Miguel; Price, Brendan D. (Cell Reports, 2022-12)DNA damage leads to rapid synthesis of poly(ADP-ribose) (pADPr), which is important for damage signaling and repair. pADPr chains are removed by poly(ADP-ribose) glycohydrolase (PARG), releasing free ...