Visualitzant Departament de Ciències Bàsiques (Biomedicina, Bioenginyeria, Psicologia) per autor/a "Universitat Internacional de Catalunya. Departament de Ciències Bàsiques"
Ara mostrant els elements 1-20 de 51
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A bioengineering approach for corneal endothelial regeneration.
Bosch Canals, Begoña María (Data de defensa: 2019-07-31)Nowadays, there are approximately 10 million people worldwide with visual impairment due to corneal diseases. Currently, the main therapeutic solution is the transplant of a donor's cornea. The great ... -
Análisis de la respuesta neuromuscular y la proyección del ángulo de la rodilla en el plano frontal en sujetos físicamente activos: implicaciones para la lesión de ligamento cruzado anterior
Llurda Almuzara, Luis (Data de defensa: 2022-09-16)La lesión de ligamento cruzado anterior es una de las lesiones más devastadoras en el ámbito deportivo. El valgo dinámico de rodilla durante el gesto deportivo puede ser uno de los mecanismos más comunes ... -
Caracterización cuantitativa de las ciclinas de la fase G1 del ciclo celular en Saccharomyces cerevisiae
Bállega Moreno, Elisabet (Data de defensa: 2017-11-07)Saccharomyces cerevisiae és un microorganisme unicel·lular eucariota que per presentar el seu genoma totalment seqüenciat, gran facilitat de manipulació en el treball de laboratori, ja que molts dels ... -
Caracterización de complejos CDK-Ciclina atípicos humanos
Quandt Herrera, Eva (Data de defensa: 2018-03-15)La desregulación en los mecanismos de control del ciclo celular es un evento indiscutiblemente asociado a la aparición de diversas patologías, entre las que destacan los procesos tumorales. Como principales ... -
Caracterización molecular de nuevos substratos de la CDK Pho85
Ricco Pacheco, Natalia (Data de defensa: 2013-07-29)La ciclina Cln3 es un activador crítico de START, cuya sobreexpresión provoca células de menor tamaño que progresan rápidamente por el ciclo celular, mientras que su deleción induce un mayor tamaño de ... -
CDK-mediated phosphorylation of Yku80 and its role in DNA repair
Carballar Ruiz, María de los Reyes (Data de defensa: 2021-03-11)DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining ... -
Characterization of new mutations in transferrin, DMT1 and SEC23B causing rare iron metabolism-related diseases; and the discovery of RACGAP1 as the gene responsible for autosomal recessive congenital dyserythropoietic anaemia type III
Romero Cortadellas, Lídia (Data de defensa: 2023-11-25)Iron is a biometal involved in many physiological processes that are essential for life. Iron metabolism is a complex and tightly regulated process both at the systemic and cellular level. Proper iron ... -
Control de la estabilidad de ciclinas de G1 por nutrientes
Hernández Ortega, Sara (Data de defensa: 2014-07-31)El control del ciclo celular está altamente regulado mediante diferentes CDKs asociadas a ciclinas. En Saccharomyces cerevisiae, la CDK esencial Cdc28 es la que regula mayoritariamente este proceso. En ... -
CPT1C and endocannabinoids as hypothalamic players in early stages of obesity development
Miralpeix Monclús, Cristina (Data de defensa: 2019-12-10)Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, ... -
CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation
Fosch Masllovet, Anna (Data de defensa: 2022-09-23)Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an ... -
CPT1C-ABHD6 interaction in hypothalamic neurons: implications for bis (monoacylglycero) phosphate metabolism and the endolysosomal system
Reguera Moreno, Ana Cristina (Data de defensa: 2024-02-14)El sistema endolisosomal juga un paper crític en la funció neuronal i ha emergit com a un potencial objectiu per al tractament de diverses malalties neuronals, com els trastorns neurodegeneratius i fins ... -
CPT1C-dependent regulation of GluA1 trafficking under metabolic stress
Casas Prat, María (Data de defensa: 2019-12-10)Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still ... -
Desarrollo de nuevos métodos para el análisis del polifosfato en células humanas
Sarrias Giménez, Ana (Data de defensa: 2023-11-20)Nombre / Nom / Name Ana Apellidos / Cognoms / Surname Sarrias Giménez Dirección de correo electrónico / Adreça de correu electrònic / email address (opcional / optional) anasargim@gmail.com Departamento ... -
Development of C75-CoA loaded polymeric micelles targeting brain CPT1A: A novel nanomedicine-based approach to fight obesity and cancer
García-Chica, Jesús (Data de defensa: 2024-02-14)Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl ... -
Development of novel bioinks formulations based on supramolecular self-assembled hydrogels for tissue regeneration.
Merino Gómez, María (Data de defensa: 2023-05-16)The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also ... -
Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering
Rodríguez González, Raquel (Data de defensa: 2023-05-31)The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body ... -
El polifosfat és un element clau durant la replicació del DNA.
Bru Rullo, Samuel (Data de defensa: 2015-11-06)Throughout its lifespan, eukaryotic cells steadily consume free cytoplasmic orthophosphate to produce phospholipids and mRNA. However, during DNA synthesis, in a matter of minutes, cells require large ... -
Estudi de la ciclina atípica CCNI com a potencial activador de CDK6 en línies de càncer de mama
Masip Sales, Núria (Data de defensa: 2022-02-09)Fa quasi 40 anys del descobriment de les ciclines, les proteïnes oscil·lants tradicionalment dividies en dos grups, “cicle cel·lular” i “ciclines transcripcionals”, que duen a terme els seus rols juntament ... -
Evaluation of biomarkers for studying new challenges in tobacco control
Pérez - Martín, Hipólito (Data de defensa: 2023-12-19)El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control ... -
Evaluation of the impact of Spanish smoking legislation on tobacco consumption and passive exposure
Lidón Moyano, Cristina (Data de defensa: 2018-03-14)In Spain, two smoke-free laws have been passed after the approval of the FCTC. In 2005, it came into effect a smoke-free legislation (Law 28/2005). This law was a great advance for public health in ...