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Dynamic force spectroscopy of DNA hairpins: I. Force kinetics and free energy landscapes
(IOP Publishing, 2009)
We investigate the thermodynamics and kinetics of DNA hairpins that fold/unfold under the action of applied mechanical force. We introduce the concept of the molecular free energy landscape and derive ...
Work distributions in the T = 0 random field Ising model
(American Physical Society, 2008)
We perform a numerical study of the three-dimensional random-field Ising model at T= 0. We compare work distributions along metastable trajectories obtained with the single-spin flip dynamics with the ...
Investigating the thermodynamics of small biosystems with optical tweezers
(Elsevier, 2010)
We present two examples of how single-molecule experimental techniques applied to biological systems can give insight into problems within the scope of equilibrium and nonequilibrium mesoscopic ...
2P-111 Stochastic resonance in DNA hairpins(The 46th Annual Meeting of the Biophysical Society of Japan)
(The Biophysical Society of Japan, 2008)
Single-molecule stochastic resonance
(American Physical Society, 2012)
Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ...
Statistical properties of metastable intermediates in DNA unzipping
(American Physical Society, 2009)
We unzip DNA molecules using optical tweezers and determine the sizes of the cooperatively unzipping and zipping regions separating consecutive metastable intermediates along the unzipping pathway. Sizes ...
Supernumerary fourth molar and dental pathologies in a Chalcolithic individual from the El Mirador Cave site (Sierra de Atapuerca, Burgos, Spain)
(Elsevier, 2015)
We present a middle-aged Chalcolithic male with a supernumerary distomolar in the mandible. The prevalence of supernumerary teeth in present-day populations is low, ranging from 0.1% to 3.4%; most ...
Root canal morphology of Chalcolithic and early bronze age human populations of El Mirador Cave (Sierra de Atapuerca, Spain)
(Wiley, 2014)
This study provides a morphological characterization of the inner anatomy of the root canals of permanent first and second molars in Chalcolithic and early Bronze Age human fossils using cone-beam ...
Microscopic and virtual approaches to oral pathology: a case study from El Mirador Cave (Sierra de Atapuerca, Spain)
(Elsevier, 2022-01)
Background: The analysis and diagnosis of ancient oral pathologies have been improved with the application of new techniques such as microscopy and scanning methods over the past few decades. However, ...
Dental and oral pathologies at El Mirador Cave (Sierra de Atapuerca, Spain)
(Springer Nature, 2022)
The dental and oral pathologies of the Chalcolithic and Early Bronze Age herders from El Mirador cave indicate good general oral health in both populations as deduced from the low prevalence of pathologies ...