Browsing Recerca by Subject "616.8"
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Applying qualitative research to develop a guide for parents of newborns with hypoxic-ischemic encephalopathy
(International Journal of Qualitative Methods, 2020-05-07)Moderate-to-severe hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal mortality and permanent disability in surviving newborns. Therapeutic hypothermia (TH) is the only effective ... -
Attachment-based compassion therapy for reducing anxiety and depression in fibromyalgia
(International Journal of Environmental Research and Public Health, 2022)Fibromyalgia patients often experience anxiety and depressive symptoms; however, validated interventions show only limited efficacy. This pilot study analyzed the effects of a 16-session version of ... -
Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway
(2009-12-15)Bone morphogenetic proteins (BMPs) have been implicated in the generation and postnatal differentiation of cerebellar granule cells (CGCs). Here, we examined the eventual role of BMPs on the survival ... -
Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases
(Scientific Reports, 2020)The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ... -
Cognitive phenotypes 1 month after ICU discharge in mechanically ventilated patients: a prospective observational cohort study
(Critical Care, 2020)Background: ICU patients undergoing invasive mechanical ventilation experience cognitive decline associated with their critical illness and its management. The early detection of different cognitive ... -
CPT1C and endocannabinoids as hypothalamic players in early stages of obesity development
(Date of defense: 2019-12-10)Obesity prevalence in worldwide population is increasing every day due to an imbalance between the energy intake and the energy expenditure. Rich-caloric food is highly palatable and easily accessible, ... -
CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation
(Date of defense: 2022-09-23)Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an ... -
CPT1C-ABHD6 interaction in hypothalamic neurons: implications for bis (monoacylglycero) phosphate metabolism and the endolysosomal system
(Date of defense: 2024-02-14)El sistema endolisosomal juga un paper crític en la funció neuronal i ha emergit com a un potencial objectiu per al tractament de diverses malalties neuronals, com els trastorns neurodegeneratius i fins ... -
CPT1C-dependent regulation of GluA1 trafficking under metabolic stress
(Date of defense: 2019-12-10)Carnitine palmitoyltransferase 1C (CPT1C) is the brain-specific isoform of the CPT1 family which is located at the endoplasmic reticulum (ER) of neurons and exhibits low catalytic activity, but still ... -
Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study
(International Journal of Infectious Diseases, 2020-08)Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ... -
Development of C75-CoA loaded polymeric micelles targeting brain CPT1A: A novel nanomedicine-based approach to fight obesity and cancer
(Date of defense: 2024-02-14)Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl ... -
Direct health costs of amyotrophic lateral sclerosis in a multidisciplinary ALS unit in Catalonia (Spain)
(Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2022)Our research project computed the direct health costs of patients with amyotrophic lateral sclerosis (ALS) in a Spanish multidisciplinary unit and explored the main factors associated. Besides analyzing ... -
Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice
(Molecular Psychiatry, 2021)Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in ... -
Efectos de la estimulación transcutánea del nervio tibial posterior en comparación a la estimulación percutánea en el síndrome de vejiga hiperactiva idiopática: Ensayo clínico aleatorizado
(Date of defense: 2017-10-23)INTRODUCCIÓN: El síndrome de vejiga hiperactiva (VH) se caracteriza clínicamente por la presencia de frecuencia miccional aumentada, nicturia, urgencia y en algunos casos incontinencia de urgencia (IUU). ... -
The effectiveness of additional core stability exercises in improving dynamic sitting balance, gait and functional rehabilitation for subacute stroke patients (CORE-Trial): study protocol for a randomized controlled trial
(International Journal of Environmental Research and Public Health, 2021) -
The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis
(International Orthopaedics, 2021)Aim of the study Systematic review and meta-analysis to assess the efectiveness of manual therapy in improving carpal tunnel syndrome (CTS) symptoms, physical function, and nerve conduction studies. ... -
Eficacia de las ondas de choque radiales en comparación con la toxina botulínica tipo A para el tratamiento de la espasticidad en las extremidades inferiores en pacientes con parálisis cerebral. ensayo clínico cruzado aleatorizado.
(Date of defense: 2017-03-21)Eficacia de las ondas de choque radiales en comparación con la toxina botulínica tipo A en el tratamiento de la espasticidad de las extremidades inferiores en pacientes con parálisis cerebral: Ensayo ... -
El médico como segunda víctima en los casos de reclamación profesional por malapraxis
(Date of defense: 2021-06-15)La primera y principal víctima de un evento adverso en la asistencia es el paciente y su entorno, sin embargo, la psicología reconoce el sufrimiento de la segunda víctima. Si dicho evento adverso se ... -
Evaluación del efecto de los ejercicios de Core Stability para mejorar el equilibrio en sedestación y control de tronco en los pacientes que han sufrido un ictus
(Date of defense: 2015-10-22)La presente tesis compila el resultado de cuatro estudios siguiendo una línea de investigación. Los cuatro articulos han sido publicados. Esta línea tiene una vertiente metodológica y otra clínica, ... -
Evaluating disease progression and care provision in Spinal Muscular Atrophy
(Date of defense: 2023-03-06)Background: Spinal Muscular Atrophy is a group of rare genetic conditions characterised by progressive muscle wasting and weakness. SMA has a heterogenous clinical presentation ranging from severe infant ...