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dc.contributor.authorSalomó-Coll, O.
dc.contributor.authorVal de Maté-Sánchez, J. E.
dc.contributor.authorRamírez-Fernandez, M. P.
dc.contributor.authorHernández-Alfaro, F.
dc.contributor.authorGargallo-Albiol, J.
dc.contributor.authorCalvo-Guirado, J. L.
dc.date.accessioned2024-01-24T11:14:17Z
dc.date.available2024-01-24T11:14:17Z
dc.date.issued2016
dc.identifier.citationSalomó-Coll, O.; Val de Maté-Sánchez, J. E.; Ramírez-Fernandez, M. P. [et al.]. Osseoinductive elements around immediate implants for better osteointegration: a pilot study in foxhound dogs. Clinical Oral Implants Research, 2016, 29(11), p. 1061-1069. Disponible en: <https://onlinelibrary.wiley.com/doi/10.1111/clr.12809>. Fecha de acceso: 24 ene. 2024. DOI: 10.1111/clr.12809ca
dc.identifier.issn0905-7161ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/3957
dc.description.abstractObjective: The aim of this study was to evaluate the effects on osseointegration of topical applications of melatonin vs. vitamin D over surfaces of immediate implants. Materials and methods: Mandibular premolar distal roots (P2 , P3 , P4 ) were extracted bilaterally from six American Foxhound dogs. Three conical immediate implants were randomly placed bilaterally in each mandible. Three randomized groups were created: melatonin 5% test group (MI), vitamin D 10% test group (DI), and Control group implants (CI). Block sections were obtained after 12 weeks and processed for mineralized ground sectioning. Bone-to-implant contact (total BIC), new bone formation (NBF), inter-thread bone (ITB), and histological linear measurements (HLM) were assessed. Results: At 12 weeks, all implants were clinically stable and histologically osseointegrated. Total BIC values were 49.20 ± 3.26 for the MI group, 49.86 ± 1.89 for DI group and 45.78 ± 4.21 for the CI group (P < 0.018) with statistically significant difference between the three groups. BIC percentage were 42.44 ± 2.18 for MI, 44.56 ± 1.08 for DI, and 41.95 ± 3.34 for CI groups respectively (P > 0.05). Inter-thread bone formation values were MI 17.56 ± 2.01, for DI 19.87 ± 0.92, and CI 14.56 ± 1.24 (P > 0.05). Statistically significant differences in peri-implant new bone formation were found between the three groups: MI 28.76 ± 1.98, DI 32.56 ± 1.11 and CI 25.43 ± 4.67, respectively (P < 0.045). Linear measurements showed that the MI group showed significantly less lingual crestal bone loss (CBL) (MI 0.59 ± 0.71), compared to DI (0.91 ± 1.21) and CI (0.93 ± 1.21) (P < 0.042), and less lingual peri-implant mucosa (PIM) (MI 3.11 ± 1.34),(DI 3.25 ± 0.18 compared with CI 3.54 ± 1.81 (P = 0.429). Linear measurements of buccal CBL showed significantly less buccal bone loss in test DI (0.36 ± 0.12) than CI (1.34 ± 1.23) and MI (1.11 ± 1.38) (P = 0.078). Conclusions: Within the limitations of this animal study, topical applications of 5% Melatonin or 10% vitamin D improved bone formation around implants placed immediately after extraction and helped to reduce CBL after 12 weeks osseointegration.ca
dc.format.extent8ca
dc.language.isoengca
dc.publisherWileyca
dc.relation.ispartofClinical Oral Implants Researchca
dc.relation.ispartofseries29;11
dc.subject.otherImplants dentalsca
dc.subject.otherContacteca
dc.subject.otherImplants immediatsca
dc.subject.otherMelatoninaca
dc.subject.otherOsteointegracióca
dc.subject.otherVitamina Dca
dc.subject.otherImplantes dentalesca
dc.subject.otherContactoca
dc.subject.otherImplantes inmediatosca
dc.subject.otherMelatoninaca
dc.subject.otherOsteointegraciónca
dc.subject.otherVitamina Dca
dc.subject.otherDental implantsca
dc.subject.otherContactca
dc.subject.otherImmediate implantsca
dc.subject.otherMelatoninca
dc.subject.otherOsseointegrationca
dc.subject.otherVitamin Dca
dc.titleOsseoinductive elements around immediate implants for better osteointegration: a pilot study in foxhound dogsca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc616.3ca
dc.identifier.doihttps://dx.doi.org/10.1111/clr.12809ca


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