Interposition of a connective tissue graft or a collagen matrix to enhance wound stability – an experimental study in dogs
Author
Burkhardt, Rino
Ruiz Magaz, Vanessa
Hämmerle, Christoph H.F.
Lang, Niklaus P.
Research Group on Oral Soft Tissue Biology & Wound Healing
Publication date
2016ISSN
0303-6979
Abstract
Aim: The aim of this study was to evaluate the role of a connective tissue graft (CTG) or a collagen matrix (CM) interpositioned between flaps and non-shedding hard surfaces on wound stability. Material and Methods: Sixty bone dehiscence defects were prepared in five Beagle dogs. Three treatments were performed in 12 sites per dog: (1) repositioned flaps were sutured onto instrumented dentin surfaces (control), (2) repositioning of flaps with an interpositioned CTG and (3) repositioning of flaps with the application of a CM. To allow postoperative healing with n = 5 for 1, 3, 7 and 14 days before evaluation, the sutures were removed, incision lines retraced and tensile forces applied to the flaps. The minimum magnitude of forces required to detach the flaps from the wound bed was recorded. Results: After 1 week of healing, 6 N had to be applied to disrupt flaps from their wound bed in the CTG group. In the control group, a similar magnitude of resistance was achieved after 2 weeks (6.1 N). Flap resistance to tearing was highest in the CTG group (maximum 9.1 N) 2 weeks postoperatively. On the third postoperative day, the mean tearing forces of all groups differed significantly, displaying a 50% lower resistance to tearing in the CM compared to the CTG group. In comparison, flap resistance to tearing forces established earlier and in higher magnitude in sites with an interpositioned CTG than in flaps repositioned on dentin or CM. Conclusions: Application of a CTG, sutured to a non-shedding hard surface, significantly increased flap resistance to tearing when applying disrupting forces compared to controls. A less pronounced effect was achieved by interpositioning of a CM.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Matriu de col·lagen
Empelt de teixit conjuntiu
Colgajo quirúrgic
Resistència a la tracció
Cicatrització de ferides
Matriz de colágeno
Injerto de tejido conectivo
Colgajo quirúrgico
Resistencia a la tracción
Curación de heridas
Collagen matrix
Connective tissue graft
Surgical flap
Tensile strength
Wound healing
Pages
7
Publisher
Wiley
Collection
43; 4
Is part of
Journal of Clinical Periodontology
Citation
Burkhardt, Rino; Ruiz Magaz, Vanessa; Hämmerle, Christoph H.F. [et al.]. Interposition of a connective tissue graft or a collagen matrix to enhance wound stability – an experimental study in dogs. Journal of Clinical Periodontology, 2016, 43(4), p. 366-373. Disponible en; <https://onlinelibrary.wiley.com/doi/10.1111/jcpe.12526>. Fecha de acceso: 22 ene. 2024. DOI: 10.1111/jcpe.12526
This item appears in the following Collection(s)
- Odontologia [248]
Rights
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd