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Enhanced osteoconductivity on electrically charged titanium implants treated by physicochemical surface modifications methods

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Gil Mur, Francisco Javier [et al.]_Enhanced Osteoconductivity Electrically_2019.pdf (2.265Mb)
Author
Fernández Yagüe, Marc
Pérez Antoñanzas, Roman
Roa, Joan Josep
Biggs, Manus
Gil Mur, Francisco Javier
PEGUEROLES, MARTA
Publication date
2019-06
URI http://hdl.handle.net/20.500.12328/2928
DOI
https://dx.doi.org/10.1016/j.nano.2019.02.005
ISSN
1549-9634
Abstract
Biomimetic design is a key tenet of orthopedic device technology, and in particular the development of responsive surfaces that promote ion exchange with interfacing tissues, facilitating the ionic events that occur naturally during bone repair, hold promise in orthopedic fixation strategies. Non-bioactive nanostructured titanium implants treated by shot-blasting and acid-etching (AE) induced higher bone implant contact (BIC=52% and 65%) compared to shot-blasted treated (SB) implants (BIC=46% and 47%) at weeks 4 and 8, respectively. However, bioactive charged implants produced by plasma (PL) or thermochemical (BIO) processes exhibited enhanced osteoconductivity through specific ionic surface-tissue exchange (PL, BIC= 69% and 77% and BIO, BIC= 85% and 87% at weeks 4 and 8 respectively). Furthermore, bioactive surfaces (PL and BIO) showed functional mechanical stability (resonance frequency analyses) as early as 4 weeks post implantation via increased total bone area (BAT=56% and 59%) ingrowth compared to SB (BAT=35%) and AE (BAT=35%) surfaces.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
61 - Medicina
616.3 - Patologia de l'aparell digestiu. Odontologia
Keywords
Titani
Funcionalització
Topografies
Reparació òssia
Càrregues elèctriques
Titanio
Funcionalización
Topografías
Reparación ósea
Cargas eléctricas
Titanium
Functionalization
Topographies
Bone repair
Electrical charges
Pages
10
Publisher
Elsevier
Collection
18;
Is part of
Nanomedicine: Nanotechnology, Biology and Medicine
Citation
Fernández-Yagüe, Marc; Perez Antoñanzas, Roman; Roa, Joan Josep [et al.]. Enhanced osteoconductivity on electrically charged titanium implants treated by physicochemical surface modifications methods, 2019, 18, p. 1-10. Disponible en: <https://www.sciencedirect.com/science/article/pii/S154996341930036X?via%3Dihub>. Fecha de acceso: 10 nov. 2021. DOI: 10.1016/j.nano.2019.02.005
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  • Odontologia [169]

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