Blood absorption capacity of different xenograft bone substitutes. An in-vitro study
Author
Ortiz-Puigpelat, Octavi
Simões, Andreia
Caballé-Serrano, Jordi
Hernández Alfaro, Federico
Publication date
2019-11ISSN
1989-5488
Abstract
Background: Commercially available xenograft blocks, claim to have adequate characteristics to interact with biological media and thus permitting biological fluid absorption. The objective of this in vitro study was to compare the blood absorption capacity of four different xenograft block materials of different composition of collagen and porosity. Material and Methods: Four brands of xenograft block materials were used (NuOss®, Bio-Oss®, Osteobiol® and Smartbone®). Five samples of each brand were analyzed, making a total of 20 tests. Human blood was used as the absorption liquid for the present experiment. The time period, in which the block remains in contact with the blood, was registered at 30 seconds (T1), 60 seconds (T2) and 5 minutes (T3). The xenograft blocks were evaluated according to their absorption capacity. Results: The absorption capacity of the different biomaterials were statistical significant different (p<0,001) at T1, T2 and T3 time points. At 30 seconds, Smartbone® absorbed significantly less blood than NuOss® and Bio-Oss®, however, without differences comparing with Osteobiol®. The NuOss®, Bio-Oss® and Osteobiol® did not register any significant difference between them. At 60 seconds, the Smartbone® absorbed significantly less blood than the other biomaterials. Conclusions: The NuOss® was significantly superior than Osteobiol®, but without differences relatively with Bio-Oss®. Also the Bio-Oss® and Osteobiol® did not register any difference between them. At 5 minutes, the Smatbone® continued to significantly absorbed less blood than any other biomaterial, nevertheless, NuOss®, Bio-Oss® and Osteobiol® not register again any significant difference between them. Despite of small sample size, it can be concluded that NuOss® was superior, in terms of blood absorption capacity, comparing with the other block biomaterials at 30 seconds, 60 seconds and 5 minutes. However, more investigation in a clinical setting are needed to know the clinical implications of the absorption capacity of such biomaterials.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
616.3 - Pathology of the digestive system. Complaints of the alimentary canal
Keywords
Absorció de sang
Osteoconducció
Xenoinjerts
Regeneració òssia
Col·lagen
Porositat
Absorción de sangre
Osteoconducción
Xenoinjerto
Regeneración ósea
Colágeno
Porosidad
Blood absorption
Osteoconduction
Xenografts
Bone regeneration
Collagen
Porosity
Pages
7
Publisher
Medicina Oral
Collection
11;11
Is part of
Journal of Clinical and Experimental Dentistry
Citation
Ortiz-Puigpelat, Octavi; Simões, Andreia; Caballé-Serrano, Jordi [et al.]. Blood absorption capacity of different xenograft bone substitutes. An in-vitro study. Journal of Clinical and Experimental Dentistry, 2019, 11(11), e-1018-1024. Disponible en: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825731/>. Fecha de acceso: 3 jun. 2021. DOI: 10.4317/jced.56317
This item appears in the following Collection(s)
- Odontologia [222]
Rights
© 2019 Medicina Oral S.L. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/