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Optimized metrics for orthogonal combinatorial CRISPR screens
(Scientific Reports, 2023)CRISPR-based gene perturbation enables unbiased investigations of single and combinatorial genotype-to-phenotype associations. In light of efforts to map combinatorial gene dependencies at scale, choosing ... -
Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study
(Health and Quality of Life Outcomes, 2023)Background: People living with HIV (PLWH) face structural and psychosocial factors that affect health-related quality of life (HRQoL). We aimed to evaluate how syndemic conditions affected HRQoL in PLWH. ... -
Precision of ultrasound-guided versus anatomical palpation-guided needle placement of the ulnar nerve at the cubital tunnel: a cadaveric study
(Healthcare, 2023)Percutaneous electrical stimulation has been performed for years with only the assistance of anatomical landmarks. The development of real-time ultrasonography guidance has improved the precision and ... -
Editorial: Methods and applications in vascular physiology: 2021
(Frontiers in Physiology, 2022)This Research Topic is a part of the Methods and Applications in Physiology series and aims at highlighting the latest experimental and computational methods in vascular physiology and their pharmacological, ... -
A Midline Maxillary Tusk-Shaped Incisor in an Infant
(Dermatology Practical & Conceptual, 2023)A 4-month-old boy, who previously presented for a sizable gingival hemangioma on the lower gingiva two months earlier and was being treated with propranolol and monthly follow-up, now presented with a ... -
Effects and safety of hypertonic saline combined with airway clearance in non-hospitalized children with recurrent wheezing
(Hong Kong Physiotherapy Journal, 2023)Background: The International Study of Wheezing in Infants defines recurrent wheezing as the presence of three or more medically documented episodes of wheezing within one year. To date, there is no ... -
A beta version of an application based on computer vision for the assessment of knee valgus angle: a validity and reliability study
(Healthcare, 2023)Background: In handball, the kinematics of the frontal plane seem to be one of the most important factors for the development of lower limb injuries. The knee valgus angle is a fundamental axis for ... -
Changes over time in the strain on the inferior ilio-femoral ligament during a sustained 5-minute high-force long axis distraction mobilization: a cadaveric study
(Archives of Physical Medicine and Rehabilitation, 2023)Objective: To analyze the changes over time in the strain on the inferior ilio-femoral (IIF) ligament when a constant high-force long-axis distraction mobilization (LADM) was applied over 5 minutes. ... -
Which athletes fail faster to send weekly questionnaires or to comply with an injury risk reduction program?
(German Journal of Sports Medicine, 2023)Problem: Low response rate to weekly self-reported questionnaires used to obtain athlete health-related and risk exposure data and low compliance with intervention have been reported. We thus aimed to ... -
Risk factors associated with inappropriate empirical antimicrobial treatment in bloodstream infections. A cohort study
(Frontiers in Pharmacology, 2023)Introduction: Bloodstream infections (BSI) are a major cause of mortality all over the world. Inappropriate empirical antimicrobial treatment (i-EAT) impact on mortality has been largely reported. ... -
Implantation of CPT1AM-expressing adipocytes reduces obesity and glucose intolerance in mice
(Metabolic Engineering, 2023-05)Obesity and its associated metabolic comorbidities are a rising global health and social issue, with novel therapeutic approaches urgently needed. Adipose tissue plays a key role in the regulation of ... -
Association between soluble angiotensin-converting enzyme 2 in saliva and SARS-CoV-2 infection: a cross-sectional study
(Scientific Reports, 2023)This study aimed to investigate the association between saliva soluble angiotensin-converting enzyme 2 (sACE2) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and ... -
Impact of the bacterial nasopharyngeal microbiota on the severity of genus enterovirus lower respiratory tract infection in children: a case–control study
(Pediatric Pulmonology, 2023)Introduction: Rhinoviruses (RV) and enteroviruses (EV) are among the main causative etiologies of lower respiratory tract infection (LRTI) in children. The clinical spectrum of RV/EV infection is wide, ... -
Determinants of depressive symptoms in people living with HIV: findings from a population-based study with a gender perspective
(International Journal of Environmental Research and Public Health, 2023)Depressive symptoms are common among people living with HIV (PLWH). The aim of this study was to identify the determinants of depressive symptoms in PLWH in Spain. A total of 1060 PLWH participated in ... -
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
(Biology of Sex Differences, 2023)Background: Fatty acid metabolism in the hypothalamus has an important role in food intake, but its specific role in AgRP neurons is poorly understood. Here, we examined whether carnitinea palmitoyltransferase ... -
A computer vision-based application for the assessment of head posture: a validation and reliability study
(Applied Sciences, 2023)As its name implies, the forward head position (FHP) is when the head is further forward of the trunk than normal. This can cause neck and shoulder tension, as well as headaches. The craniovertebral ... -
Physical and mental health impact of the COVID-19 pandemic at first year in a Spanish adult cohort
(Scientific Reports, 2023)The COVID-19 pandemic and the political and health measures have profoundly affected the health of our populations. However, very few studies have been published assessing its impact using a prospective ... -
SARS-CoV-2 transmission in teenagers and young adults in Fútbol Club Barcelona’s multidisciplinary sports training academy
(European Journal of Pediatrics, 2023)Most studies, aimed at determining the incidence and transmission of SARS-CoV-2 in children and teenagers, have been developed in school settings. Our study conducted surveillance and inferred attack ... -
Efficacy of virtual reality simulation in teaching basic life support and its retention at 6 months
(International Journal of Environmental Research and Public Health, 2023)Educational efficiency is the predetermining factor for increasing the survival rate of patients with cardiac arrest. Virtual reality (VR) simulation could help to improve the skills of those undergoing ... -
A novel device for assessment and treatment of upper cervical spine: test–retest reliability study
(Journal of Clinical Medicine, 2023)Introduction: Neck pain is one of the most frequent reasons for consultation in primary care. Clinicians evaluate different variables, including movement and cervical strength, to determine the prognosis ...