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Now showing items 181-190 of 602
Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
(John Wiley & Sons, Inc., 2020)
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high‐fat ...
Does upper cervical manual therapy provide additional benefit in disability and mobility over a physiotherapy primary care program for chronic cervicalgia? A randomized controlled trial
(MDPI, 2020-11-11)
Introduction: Neck pain is a condition with a high incidence in primary care. Patients with chronic neck pain often experience reduction in neck mobility. However, no study to date has investigated the ...
Impacto de la crisis económica en la actividad y eficiencia de un hospital terciario universitario
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Fundamentos: La crisis económica iniciada el año 2008 provocó una caída importante del gasto sanitario público en España. El objetivo del estudio fue evaluar el impacto de la crisis en la actividad, ...
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts
(Public Library of Science, 2019)
Pulmonary fibrosis (PF) is the result of chronic injury where fibroblasts become activated and secrete large amounts of extracellular matrix (ECM), leading to impaired fibroblasts degradation followed ...
COVID-19: making the best out of a forced transition to online medical teaching. A mixed methods study
(Springer, 2021)
Introduction the COVID-19 pandemic resulted in a decreed confinement in our country from March until the end of term in June 2020. This forced a transition exclusively to distance learning. The aim of ...
Cpt1c downregulation causes plasma membrane remodelling and anthracycline resistance in breast cancer
(MDPI, 2023)
Breast cancer (BC) is the most common malignancy in women worldwide. While the main systemic treatment option is anthracycline-containing chemotherapy, chemoresistance continues to be an obstacle to ...
Individual prevention and containment measures in schools in Catalonia, Spain, and community transmission of SARS-CoV-2 after school re-opening
(Public Library of Science, 2022)
Background: Despite their clear lesser vulnerability to COVID-19, the extent by which children are susceptible to getting infected by SARS-CoV-2 and their capacity to transmit the infection to other ...
Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona, Spain
(Wolters Kluwer, 2017-07)
Cohort studies of large series of patients with sarcoidosis over a long period of time are scarce. The aim of this study is to report a 40-year clinical experience of a large series of patients at ...
Susceptibility to severe acute respiratory syndrome coronavirus 2 infection among children and adults: a seroprevalence study of family households in the Barcelona metropolitan region, Spain
(Oxford University Press, 2021-06)
Background: Susceptibility of children and adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and persistence of antibody response to the virus after infection resolution ...
Proactive and systematic multidimensional needs assessment in patients with advanced cancer approaching palliative care: a study protocol
(BMJ Publishing Group, 2020)
Introduction The benefits of palliative care rely on how healthcare professionals assess patients’ needs in the initial encounter/s; crucial to the design of a personalised therapeutic plan. However, ...