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Attachment-based compassion therapy for reducing anxiety and depression in fibromyalgia
(MDPI, 2022)
Fibromyalgia patients often experience anxiety and depressive symptoms; however, validated interventions show only limited efficacy. This pilot study analyzed the effects of a 16-session version of ...
Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases
(Springer Nature, 2020)
The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ...
Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway
(Molecular biology of the cell, 2009-12-15)
Bone morphogenetic proteins (BMPs) have been implicated in the generation and postnatal differentiation of cerebellar granule cells (CGCs). Here, we examined the eventual role of BMPs on the survival ...
Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study
(Elsevier, 2020-08)
Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ...
The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis
(Springer, 2021)
Aim of the study Systematic review and meta-analysis to assess the efectiveness of manual therapy in improving carpal tunnel syndrome (CTS) symptoms, physical function, and nerve conduction studies. ...
Genetic and clinical heterogeneity in thirteen new cases with aceruloplasminemia. Atypical anemia as a clue for an early diagnosis
(MDPI, 2020)
Aceruloplasminemia is a rare autosomal recessive genetic disease characterized by mild microcytic anemia, diabetes, retinopathy, liver disease, and progressive neurological symptoms due to iron accumulation ...
Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016
(European Centre for Disease Prevention and Control (ECDC), 2019-02)
Enterovirus 71 (EV-A71) is a small, non-enveloped, single-stranded RNA virus that belongs to the species Enterovirus A along with 24 other serotypes within the Enterovirus genus [1]. According to the ...
Machine learning to understand the immune-inflammatory pathways in fibromyalgia
(MDPI, 2019)
Fibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, and physical and emotional symptoms. Although its pathophysiology is largely unknown, immune-inflammatory pathways ...
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Rockefeller University Press, 2020)
Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
Cognitive phenotypes 1 month after ICU discharge in mechanically ventilated patients: a prospective observational cohort study
(Springer Nature, 2020)
Background: ICU patients undergoing invasive mechanical ventilation experience cognitive decline associated with their critical illness and its management. The early detection of different cognitive ...