Browsing Ciències de la Salut by Author "Hernández-Ortega, Sara"

Now showing items 1-2 of 2

    • CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation 

      Quandt, Eva; Masip, Núria; Hernández-Ortega, Sara; Sánchez-Botet, Abril; Gasa, Laura; Fernández-Elorduy, Ainhoa; Plutta, Sara; Martínez-Láinez, Joan Marc; Bru, Samuel; Munoz-Torres, Pau M.; Floor, Martin; Villà-Freixa, Jordi; Morris, May C.; Vidal, August; Villanueva, Alberto; Clotet, Josep; Ribeiro, Mariana P. C. (Molecular Oncology, 2023)
      Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...

    • Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation 

      Hernández-Ortega, Sara; Bru Rullo, Samuel; Ricco Pacheco, Natalia; Ramírez, Sara; Casals i Farré, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet Erra, Josep (Journal of Biological Chemistry, 2013-02)
      Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ...