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Iron-regulatory proteins limit hypoxia-inducible factor 2α expression in iron deficiency
(Springer Nature, 2007)
Hypoxia stimulates erythropoiesis, the major iron-utilization pathway. We report the discovery of a conserved, functional iron-responsive element (IRE) in the 5′ untranslated region of the messenger RNA ...
Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays
(Springer Nature, 2007)
RNA-binding proteins (RBPs) frequently regulate the post-transcriptional fate of target mRNAs. To identify novel target mRNAs of RBPs, we incubate total RNA with recombinant RBP and immunoselect the ...