Browsing Articles by Subject "Genomic instability"
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Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
(Nature Communications, 2018)BRCA1 is a tumor suppressor that regulates DNA repair by homologous recombination. Germline mutations in BRCA1 are associated with increased risk of breast and ovarian cancer and BRCA1 deficient tumors ...