Now showing items 1-7 of 7

    • Comprehensive and quantitative analysis of G1 cyclins. A tool for studying the cell cycle 

      Ballega, Elisabet; Carballar Ruiz, María de los Reyes; Samper Martín, Bàrbara; Ricco Pacheco, Natalia; Ribeiro, Mariana P. C.; Bru Rullo, Samuel; Jiménez, Javier; Clotet Erra, Josep (PLoS One, 2019-06-25)
      In eukaryotes, the cell cycle is driven by the actions of several cyclin dependent kinases (CDKs) and an array of regulatory proteins called cyclins, due to the cyclical expression patterns of the latter. ...
    • Effect of the nature of the particles released from bone level dental implants: physicochemical and biological characterization 

      Vara, Juan Carlos; Delgado, Juan; Estrada-Martínez, Alejandro; Pérez-Pevida, Esteban; Brizuela Velasco, Aritza; Bosch Canals, Begoña Maria; Pérez, Román; Gil Mur, Francisco Javier (Coatings, 2022)
      The placement of bone–level dental implants can lead to the detachment of particles in the surrounding tissues due to friction with the cortical bone. In this study, 60 bone–level dental implants were ...
    • Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters 

      Nacht, Ana Silvina; Pohl, Andy; Zaurín Quer, Roser; Soronellas, Daniel; Quilez Oliete, Javier; SHARMA, PRIYANKA; Wright, Roni; Beato, Miguel; Vincent, Guillermo P. (The EMBO Journal, 2016)
      Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is ...
    • Osteoblastic cell behavior and gene expression related to bone metabolism on different titanium surfaces 

      Velasco-Ortega, Eugenio; Fos-Parra, Isabel; Cabanillas-Balsera, Daniel; Gil, FJ; Ortiz-García, Iván; Giner, Mercè; Bocio-Núñez, Jesús; Montoya-García, María-José; Jiménez-Guerra, Álvaro (International Journal of Molecular Sciences, 2023)
      The surface topography of titanium dental implants has a great influence on osseointegration. In this work, we try to determine the osteoblastic behavior and gene expression of cells with different ...
    • SIREs: searching for iron-responsive elements 

      Campillos, Monica; Cases, Ildefonso; Hentze, Matthias W.; Sanchez, Mayka (Nucleic Acids Research, 2010-07)
      The iron regulatory protein/iron-responsive element regulatory system plays a crucial role in the post-transcriptional regulation of gene expression and its disruption results in human disease. IREs are ...
    • Unliganded progesterone receptor governs estrogen receptor gene expression by regulating DNA methylation in breast cancer cells 

      Verde, Gaetano; Lara, de Llobet; Wright, Roni; Quilez, Javier; Peiró, Sandra; Le Dily, François; Beato, Miguel (Cancers, 2018)
      Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ...
    • Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation 

      Lamarca Dams, Aloa; Gella Concustell, Alejandro; Martiáñez Canales, Tània; Segura Castell, Mónica; Figueiro-Silva, Joana; Grijota Martínez, Maria del Carmen; Trullás, Ramón; Casals i Farré, Núria (PLoS One, 2014-06-06)
      In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5′-triphosphate ...