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PLA-based mineral-doped scaffolds seeded with human periapical cyst-derived MSCs: a promising tool for regenerative healing in dentistry 

Tatullo, Marco; Spagnuolo, Gianrico; Codispoti, Bruna; Zamparini, Fausto; Zhang, Anqi; Degli Esposti, Micaela; Aparicio, Conrado; Rengo, Carlo; Nuzzolese, Manuel; Manzoli, Lucia; Fava, Fabio; Prati, Carlo; Fabbri, Paola; Giovanna Gandolfi, Maria (MDPI, 2019)
Human periapical cyst mesenchymal stem cells (hPCy-MSCs) are a newly discovered cell population innovatively collected from inflammatory periapical cysts. The use of this biological waste guarantees a ...
 

Functional signatures of ex-vivo dental caries onset 

Moussa, Dina; Sharma, Ashok K.; Mansour, Tamer; Witthuhn, Bruce; Perdigao, Jorge; Rudney, Joel D.; Aparicio, Conrado; Gomez, Andres (Taylor & Francis Group, 2022)
Background: The etiology of dental caries remains poorly understood. With the advent of next-generation sequencing, a number of studies have focused on the microbial ecology of the disease. However, ...
 

Discerning the subfibrillar structure of mineralized collagen fibrils: a model for the ultrastructure of bone 

Li, Yuping; Aparicio, Conrado (Public Library of Science, 2013)
Biomineralization templated by organic molecules to produce inorganic-organic nanocomposites is a fascinating example of nature using bottom-up strategies at nanoscale to accomplish highly ordered ...
 

Antimicrobial GL13K peptide coatings killed and ruptured the wall of streptococcus gordonii and prevented formation and growth of biofilms 

Chen, Xi; Hirt, Helmut; Li, Yuping; Ulrik Gorr, Sven; Aparicio, Conrado (Public Library of Science, 2014)
Infection is one of the most prevalent causes for dental implant failure. We have developed a novel antimicrobial peptide coating on titanium by immobilizing the antimicrobial peptide GL13K. GL13K was ...
 

Surface immobilization chemistry of a laminin-derived peptide affects keratinocyte activity 

Fischer, Nicholas; He, Jiahe; Aparicio, Conrado (MDPI, 2020)
Many chemical routes have been proposed to immobilize peptides on biomedical device surfaces, and in particular, on dental implants to prevent peri-implantitis. While a number of factors affect peptide ...
 

Human whole blood interactions with craniomaxillofacial reconstruction materials: exploring In vitro the role of blood cascades and leukocytes in early healing events 

Lopes, Viviana; Birgersson, Ulrik; Anand, Vivek; Hulsart-Billström, Gry; Gallinetti, Sara; Aparicio, Conrado; Hong, Jaan (MDPI, 2023)
The present study investigated early interactions between three alloplastic materials (calcium phosphate (CaP), titanium alloy (Ti), and polyetheretherketone (PEEK) with human whole blood using an ...
 

Guiding bone formation using semi-onlay calcium phosphate implants in an ovine calvarial model 

Hulsart-Billström, Gry; Lopes, Viviana; Illies, Christopher; Gallinetti, Sara; Aberg, Jonas; Engqvist, Hakan; Aparicio, Conrado; Larsson, Sune; Burenstam Linder, Lars; Birgersson, Ulrik (John Wiley & Sons, 2022)
The restoration of cranio-maxillofacial deformities often requires complex reconstructive surgery in a challenging anatomical region, with abnormal soft tissue structures and bony deficits. In this ...
 

Relevant aspects of piranha passivation in Ti6Al4V alloy dental meshes 

Cruz, Nuno; Gil Mur, Francisco Javier; Punset fuste, Miquel; Manero, José María; tondela, joão paulo; Verdeguer, Pablo; Aparicio, Conrado; Ruperez, Elisa (MDPI, 2022)
Passivation of titanium alloy dental meshes cleans their surface and forms a thin layer of protective oxide (TiO2) on the surface of the material to improve resistance to corrosion and prevent release ...
 

Influence of titanium surface residual stresses on osteoblastic response and bacteria colonization 

Pereira, Rita; Maia, Paulo; Ríos-Santos, JV; Herrero-Climent, Mariano; Ríos Carrasco, Blanca; Aparicio, Conrado; Gil, FJ (MDPI, 2024)
Grit basting is the most common process applied to titanium dental implants to give them a roughness that favors bone colonization. There are numerous studies on the influence of roughness on osseointegration, ...
 

Development of standard protocols for biofilm-biomaterial interface testing 

Cieplik, Fabian; Aparicio, Conrado; Kreth, Jens; Schmalz, Gottfried (Elsevier, 2022)
The oral biofilm is associated with the most common oral diseases such as caries, periodontitis, and peri-implantitis. It is also linked to failures of dental treatment approaches (eg, direct or indirect ...
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Aparicio, Conrado (19)
Fischer, Nicholas G. (4)Li, Yuping (3)Birgersson, Ulrik (2)Chen, Xi (2)Gil, FJ (2)Hulsart-Billström, Gry (2)Lopes, Viviana (2)Mutreja, Isha (2)Zhang, Anqi (2)... Show moreSubject616.3 - Pathology of the digestive system. Complaints of the alimentary canal (19)Dental implants (4)Implantes dentales (4)Implants dentals (4)Titani (4)Titanio (4)Titanium (4)Alliberament d'ions (2)Corrosion resistance (2)Dentistry (2)... Show moreIssue Date2020 - 2025 (15)2013 - 2019 (4)
UIC Barcelona
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With collaboration of
CSUC