Now showing items 1-11 of 11

    • Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project 

      Bennett, Julia C.; Hetrich, Marissa K.; Garcia Quesada, Maria; Sinkevitch, Jenna N.; Deloria Knoll, Maria; Feikin, Daniel R.; Zeger, Scott L.; Kagucia, Eunice W.; Cohen, Adam L.; Ampofo, Krow; Brandileone, Maria-Cristina; Bruden, Dana; Camilli, Romina; Castilla, Jesús; Chan, Guanhao; Cook, Heather; Cornick, Jennifer E.; Dagan, Ron; Dalby, Tine; Danis, Kostas; De Miguel, Sara; De Wals, Philippe; Desmet, Stefanie; Georgakopoulou, Theano; Gilkison, Charlotte; Grgic-Vitek, Marta; Hammitt, Laura L.; Hilty, Markus; Ho, Pak-Leung; Jayasinghe, Sanjay; Kellner, James D.; Kleynhans, Jackie; Knol, Mirjam J.; Kozakova, Jana; Kristinsson, Karl G.; Ladhani, Shamez N.; MacDonald, Laura; Mackenzie, Grant A.; Mad’arová, Lucia; McGeer, Allison; Mereckiene, Jolita; Morfeldt, Eva; Mungun, Tuya; Muñoz-Almagro, Carmen; Nuort, J. Pekka; Paragi, Metka; Pilishvili, Tamara; Puentes, Rodrigo; Saha, Samir K.; Sahu Khan, Aalisha; Savrasova, Larisa; Scott, J. Anthony; Skoczynska, Anna; Suga, Shigeru; Van Der Linden, Mark; Verani, Jennifer R.; Von Gottberg, Anne; Winje, Brita A.; Yildirim, Inci; Zerouali, Khalid; Hayford, Kyla; PSERENADE Team (Microorganisms, 2021)
      Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. ...
    • Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study 

      Boix-Palop, Lucía; Fernández, Tamara; Pelegrín, Iván; Obradors, Meritxell; García-Roulston, Kevin; Xercavins Valls, Mariona; García-Somoza, Dolors; Ardanuy, Carmen; Grau, Javier; Calbo Sebastián, Esther; Cabellos, Carmen (International Journal of Infectious Diseases, 2020-08)
      Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ...
    • Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study 

      WLo, Stephanie; Mellor, Kate; Cohen, Robert; Redin Alonso, Alba; Belman, Sophie; Kumar, Narender; Hawkins, Paulina A.; Gladstone, Rebecca A.; Von Gottberg, Anne; Veeraraghavan, Balaji; Ravikumar, K. L.; Kandasamy, Rama; Pollard, Andrew J.; Saha, Samir K.; Bigogo, Godfrey; Antonio, Martin; Kwambana-Adams, Brenda; Mirza, Shaper; Shakoor, Sadia; Nisar, Imran; Cornick, Jennifer E.; Lehmann, Deborah; Ford, Rebecca L.; Sigauque, Betuel; Turner, Paul; Moïsi, Jennifer; Obaro, Stephen K.; Dagan, Ron; Diawara, Idrissa; Skoczyńska, Anna; Wang, Hui; Carter, Philip E.; Klugman, Keith P.; Rodgers, Gail; Breiman, Robert F.; McGee, Lesley; Bentley, Stephen D.; Muñoz-Almagro, Carmen; Varon, Emmanuelle; The Global Pneumococcal Sequencing Consortium (The Lancet Microbe, 2022-10)
      Background: Serotype 24F is one of the emerging pneumococcal serotypes after the introduction of pneumococcal conjugate vaccine (PCV). We aimed to identify lineages driving the increase of serotype 24F ...
    • Enfermedad neumocócica invasiva en niños menores de 60 meses, antes y después de la introducción de la vacuna conjugada 13-valente 

      Martínez-Osorio, Johanna; García-García, Juan José; Moraga-Llop, Fernando; Díaz, Alvaro; Hernández, Sergi; Solé-Ribalta, Anna; González-Peris, Sebastià; Izquierdo, Conchita; Esteva, Cristina; Codina, Gemma; Planes, Ana María; Uriona, Sonia; Campins, Magda; Ciruela, Pilar; Sallera, Luis; Domínguez, Ángela; Muñoz-Almagro, Carmen; De Sevilla, Mariona F. (Anales de Pediatría, 2021)
      Introducción: La enfermedad neumocócica invasiva (ENI) es la infección bacteriana más relevante en niños pequeños y la introducción de las vacunas antineumocócicas conjugadas (VNC) ha cambiado su ...
    • Nasopharyngeal microbiota in children with invasive pneumococcal disease: identification of bacteria with potential disease-promoting and protective effects 

      Camelo-Castillo, Anny; Henares, Desirée; Brotons, Pedro; Galiana, Antonio; Rodríguez, Juan Carlos; Mira, Alex; Muñoz-Almagro, Carmen; Catalan Study Group of Host- Pathogen Interaction in Patients With IPD (Frontiers in Microbiology, 2019)
      Background and Aims: The risk of suffering from some infectious diseases can be related to specific microbiota profiles. Specifically, the nasopharyngeal microbiota could play a role as a risk or ...
    • Pneumococcal serotypes in children, clinical presentation and antimicrobial susceptibility in the PCV13 era 

      Izquierdo, Conchita; Ciruela, Pilar; Hernández, Sergi; García-García, Juan José; Esteva, Cristina; Moraga-Llop, Fernando; Díaz-Conradi, A.; Martínez-Osorio, Johanna; Solé-Ribalta, Anna; De Sevilla, Mariona F.; González-Peris, Sebastià; Codina, Gemma; Planes, Ana María; Uriona, Sonia; Campins, Magda; Muñoz-Almagro, Carmen; Salleras, Luis; Domínguez, Ángela (Epidemiology and Infection, 2020-11)
      The aim was to analyse invasive pneumococcal disease (IPD) serotypes in children aged ⩽17 years according to clinical presentation and antimicrobial susceptibility. We conducted a prospective study ...
    • Rapid identification, capsular typing and molecular characterization of streptococcus pneumoniae by using whole genome nanopore sequencing 

      Garcia-Garcia, Selene; Perez-Arguello, A.; Henares, Desirée; Timoneda, N.; Muñoz-Almagro, Carmen (BMC Microbiology, 2020)
      Background: Whole genome sequencing has emerged as a useful tool for identification and molecular characterization of pathogens. MinION (Oxford Nanopore) is a real-time third generation sequencer whose ...
    • Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome 

      Dietl, Beatriz; Henares, Desirée; Boix-Palop, Lucía; Muñoz-Almagro, Carmen; Garau, Javier; Calbo Sebastián, Esther (Frontiers in Medicine, 2021-04)
      Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main ...
    • Serotype distribution of remaining pneumococcal meningitis in the mature PCV10/13 period: findings from the PSERENADE project 

      Garcia Quesada, Maria; Yang, Yangyupei; Bennett, Julia C.; Hayford, Kyla; Zeger, Scott L.; Feikin, Daniel R.; Peterson, Meagan E.; Cohen, Adam L.; Almeida, Samanta C. G.; Ampofo, Krow; Ang, Michelle; Bar-Zeev, Naor; Bruce, Michael G.; Camilli, Romina; Chanto Chacón, Grettel; Ciruela, Pilar; Cohen, Cheryl; Corcoran, Mary; Dagan, Ron; De Wals, Philippe; Desmet, Stefanie; Diawara, Idrissa; Gierke, Ryan; Guevara, Marcela; Hammitt, Laura L.; Hilty, Markus; Ho, Pak-Leung; Jayasinghe, Sanjay; Kleynhans, Jackie; Kristinsson, Karl G.; Ladhani, Shamez N.; McGeer, Allison; Mwenda, Jason M.; Nuort, J. Pekka; Oishi, Kazunori; Ricketson, Leah J.; Sanz, Juan Carlos; Savrasova, Larisa; Setchanova, Lena Petrova; Smith, Andrew; Valentiner-Branth, Palle; Valenzuela, Maria Teresa; Van der Linden, Mark; Van Sorge, Nina M.; Varon, Emmanuelle; Winje, Brita A.; Yildirim, Inci; Zintgraff, Jonathan; Knoll, Maria Deloria; PSERENADE Team (Microorganisms, 2021)
      Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the ...
    • Serotypes and clonal composition of streptococcus pneumoniae isolates causing IPD in children and adults in Catalonia before 2013 to 2015 and after 2017 to 2019 systematic introduction of PCV13 

      Redin, A.; Ciruela, P.; De Sevilla, M. F.; Gomez-Bertomeu, F.; Gonzalez-Peris, S.; Benitez, M. A.; Trujillo, G.; Diaz, A.; Jou, E.; Izquierdo, C.; Perez-Moreno, M. O.; Moraga-Llop, F.; Olsina, M.; Vinado, B.; Sanfeliu, E.; Garcia, A.; Gonzalez-di Lauro, S.; Garcia-Garcia, J. J.; Dominguez, A.; Sa-Leao, R.; Muñoz Almagro, Carmen; Catalan Study Group of Invasive Pneumococcal DiseaseSHOW FEWER (Microbiology Spectrum, 2021)
      The goal of this study was to investigate the distribution of serotypes and clonal composition of Streptococcus pneumoniae isolates causing invasive pneumococcal disease (IPD) in Catalonia, before and ...
    • Synergistic inhibition of pneumococcal growth by Dolosigranulum pigrum and Corynebacterium pseudodiphtheriticum: insights into nasopharyngeal microbial interactions 

      Cisneros Pérez, Maria; Blanco-Fuertes, Miguel; Lluansí, Aleix; Brotons de los Reyes, Pedro; Henares Bonilla , Desirée; Perez-Arguello, Amaresh; González-Comino, Gerard; Ciruela, Pilar; Mira, Alex; Muñoz-Almagro, Carmen (Microbiology Spectrum, 2025-05-30)
      ABSTRACT Streptococcus pneumoniae is a nasopharynx colonizer that can invade sterile tissues, causing invasive pneumococcal disease (IPD). Dolosigranulum pigrum and Corynebacterium pseudodiphtheriticum ...