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    • Impact of the 13-valent conjugated pneumococcal vaccine on the direct costs of invasive pneumococcal disease requiring hospital admission in children aged < 5 years: a prospective study 

      Hernández, Sergi; Navas, Encarna; Aznar-Lou, Ignacio; Ciruela, Pilar; García-García, Juan José; Moraga-Llop, Fernando; Muñoz-Almagro, Carmen; Codina, Gemma; De Sevilla, Mariona F.; González-Peris, Sebastià; Esteva, Cristina; Planes, Ana María; Izquierdo, Conchita; Martínez-Osorio, Johanna; Campins, Magda; Uriona, Sonia; Salleras, Luis; Serrano-Blanco, Antoni; Jané, Mireia; Domínguez, Ángela (Vaccines, 2020)
      The lack of invasive pneumococcal disease (IPD) cost studies may underestimate the eect of pneumococcal polysaccharide conjugated vaccines (PCV). The objective of this study was to estimate the direct ...
    • Pneumococcal nasopharyngeal carriageamong Bhutanese children hospitalizedwith clinical pneumonia: serotypes andviral co-infection 

      Jullien, Sophie; Sharma, Ragunath; Lhamu Mynak, Mimi; Henares, Desirée; Muñoz-Almagro, Carmen; Bassat, Quique (BMC Infectious Diseases, 2020-12)
      Background: Pneumococcal nasopharyngeal colonization (PNC) generally precedes pneumococcal disease. The purpose of this study was to determine the prevalence of PNC and to identify the pneumococcal ...
    • Rapid identification, capsular typing and molecular characterization of streptococcus pneumoniae by using whole genome nanopore sequencing 

      Garcia-Garcia, Selene; Perez-Arguello, A.; Henares, Desirée; Timoneda, N.; Muñoz-Almagro, Carmen (BMC Microbiology, 2020)
      Background: Whole genome sequencing has emerged as a useful tool for identification and molecular characterization of pathogens. MinION (Oxford Nanopore) is a real-time third generation sequencer whose ...
    • Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): surveillance data from 23 sites in Catalonia, Spain 

      Ludwig, Guillermo; Garcia-Garcia, Selene; Lanaspa, Miguel; Ciruela, Pilar; Esteva, Cristina; Fernandez de Sevilla, Mariona; Diaz-Conradi, Alvaro; Marti, Carmina; Motje, Montse; Galles, Carme; Morta, Montse; Izquierdo, Conchita; Moraga-Llop, Fernando; Campins, Magda; Salleras, Luis; Jané, Mireia; Domínguez, Ángela; Garcia-Garcia, Juan Jose; Muñoz-Almagro, Carmen; Catalan Study Group of Invasive Pneumococcal Disease (PLoS One, 2020-02)
      Background: The objective of this study is to describe incidence and shifts of serotype and clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups (<5 years, 5–17 ...
    • Validation of a loop-mediated isothermal amplification assay for rapid diagnosis of invasive pneumococcal disease 

      De Paz, Héctor David; Brotons, Pedro; Esteva, Cristina; Muñoz-Almagro, Carmen (Frontiers in Cellular and Infection Microbiology, 2020-03-24)
      Current molecular PCR-based techniques used for detecting Streptococcus pneumoniae, the causative pathogen of invasive pneumococcal disease (IPD), are accurate but have a run time of several hours. We ...
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