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Browsing by Subject "Mecanismes de la malaltia"

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    • Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype 

      Maus, Mate; López Polo, Vanessa; Mateo, Lidia; Lafarga, Miguel; Aguilera, Mònica; De Lama, Eugenia; Meyer, Kathleen; SOLA, ANNA; Lopez-Martinez, Cecilia; López-Alonso, Ines; Guasch-Piqueras, Marc; Hernandez-Gonzalez, Fernanda; Chaib, Selim; Rovira, Miguel; Sanchez-Fernandez, Mayka; Faner, Rosa; Agusti, Alvar; Diéguez-Hurtado, Rodrigo; Ortega, Sagrario; Manonelles, Anna; Engelhardt, Stefan; Monteiro, Freddy; Stephan-Otto Attolini, Camille; Prats, Neus; M. Albaiceta, Guillermo; CRUZADO, JOSEP M; Serrano, Manuel (Nature Metabolism, 2023)
      Fibrogenesis is part of a normal protective response to tissue injury that can become irreversible and progressive, leading to fatal diseases. Senescent cells are a main driver of fibrotic diseases ...