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Browsing by Subject "Còlon--Càncer"

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    • A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer 

      Margalef, Pol; Fernández-Majada, Vanessa; Villanueva, Alberto; Garcia-Carbonell, Ricard; Iglesias, Mar; López, Laura; Martínez-Iniesta, María; Villà-Freixa, Jordi; Mulero, Mari Carmen; Andreu, Montserrat; Torres, Ferran; Mayo, Marty W.; Bigas, Anna; Espinosa, Lluis (Cell Reports, 2012-10-25)
      Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ...