Browsing by Subject "Aminoácidos -- Metabolismo"

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Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition

Morillas, Montserrat; Gómez-Puertas, Paulino; Bentebibel, Assia; Sellés, Eva; Casals i Farré, Núria; Valencia, Alfonso; Hegardt, Fausto G.; Asins, Guillermina; Serra, Dolors (Journal of Biological Chemistry, 2003-03-14)

Carnitine palmitoyltransferase (CPT) I, which catalyzes the conversion of palmitoyl-CoA to palmitoylcarnitine facilitating its transport through the mitochondrial membranes, is inhibited by malonyl-CoA. ...