Browsing by Author "Manosas, M."

Now showing items 1-4 of 4

    • Dynamic force spectroscopy of DNA hairpins: I. Force kinetics and free energy landscapes 

      Mossa, A.; Manosas, M.; Forns, N.; Huguet Casades, Josep Maria; Ritort, F. (Journal of Statistical Mechanics: Theory and Experiment, 2009)
      We investigate the thermodynamics and kinetics of DNA hairpins that fold/unfold under the action of applied mechanical force. We introduce the concept of the molecular free energy landscape and derive ...

    • Dynamic force spectroscopy of DNA hairpins: II. Irreversibility and dissipation 

      Manosas, M.; Mossa, A.; Forns, N.; Huguet Casades, Josep Maria; Ritort, F. (Journal of Statistical Mechanics: Theory and Experiment, 2009)
      We investigate irreversibility and dissipation in single molecules that cooperatively fold/unfold in a two-state manner under the action of mechanical force. We apply path thermodynamics to derive ...

    • Improving signal/noise resolution in single-molecule experiments using molecular constructs with short handles 

      Forns, N.; de Lorenzo, S.; Manosas, M.; Hayashi, K.; Huguet Casades, Josep Maria; Ritort, F. (Biophysical Journal, 2011)
      We investigate unfolding/folding force kinetics in DNA hairpins exhibiting two and three states with newly designed short dsDNA handles (29 bp) using optical tweezers. We show how the higher stiffness ...

    • Single-molecule stochastic resonance 

      Hayashi, K.; de Lorenzo, S.; Manosas, M.; Huguet Casades, Josep Maria; Ritort, F. (Physical Review X, 2012)
      Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ...