Browsing by Author "James Dickson, Eamonn"

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    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas, Maria; Rut, Fadó; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan, Shigeru; Solé, Montse; Unzeta, Mercedes; Miñano Molina, Alfredo Jesús; Rodríguez-Álvarez, José; James Dickson, Eamonn; Casals i Farré, Núria (Journal of Cell Biology, 2020-09)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...