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Now showing items 481-500 of 3407

    • CDK-mediated Yku80 phosphorylation regulates the balance between non-homologous end joining (NHEJ) and homologous directed recombination (HDR) 

      Carballar, Reyes; Martínez-Láinez, Joan M.; Samper, Bàrbara; Bru, Samuel; Bállega, Elisabet; Mirallas, Oriol; Ricco, Natalia; Clotet, Josep; Jiménez, Javier (Journal of Molecular Biology, 2020)
      There are two major pathways for repairing DNA double-strand breaks (DSBs): homologous directed recombination (HDR) and non-homologous end-joining (NHEJ). While NHEJ functions throughout the cell cycle, ...

    • CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation 

      Quandt, Eva; Masip, Núria; Hernández-Ortega, Sara; Sánchez-Botet, Abril; Gasa, Laura; Fernández-Elorduy, Ainhoa; Plutta, Sara; Martínez-Láinez, Joan Marc; Bru, Samuel; Munoz-Torres, Pau M.; Floor, Martin; Villà-Freixa, Jordi; Morris, May C.; Vidal, August; Villanueva, Alberto; Clotet, Josep; Ribeiro, Mariana P. C. (Molecular Oncology, 2023)
      Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...

    • CDKN1A/p21 in breast cancer: part of the problem, or part of the solution? 

      Manousakis, Evangelos; Martinez Miralles, Clàudia; Guimerà Esquerda, Maria; Wright, Roni H. G. (International Journal of Molecular Sciences, 2023)
      Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ...

    • Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis 

      Castellanos, Maria Isabel; Guillem-Marti, Jordi; Mas-Moruno, Carlos; DIAZ-RICART, MARIBEL; Escolar Albaladejo, Ginés; Ginebra, Maria-Pau; Gil Mur, Francisco Javier; PEGUEROLES, MARTA; Manero, José María (Journal of biomedical materials research. Part A, 2017)
      Immobilization of bioactive peptide sequences on CoCr surfaces is an effective route to improve endothelialization, which is of great interest for cardiovascular stents. In this work, we explored the ...

    • Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy 

      Pascual, Tomás; Fernandez-Martinez, Aranzazu; Agrawal, Yash; Pfefferle, Adam D.; Chic, Nuria; Brasó-Maristany, Fara; Gonzàlez-Farré, Blanca; Paré, Laia; Villacampa, Guillermo; Saura, Cristina; Hernando, Cristina; Muñoz, Montserrat; Galván, Patricia; Gonzàlez-Farré, Xavier; Oliveira, Mafalda; Gil-Gil, Miguel; Ciruelos, Eva; Villagrasa, Patricia; Gavilá, Joaquín; Prat, Aleix; Perou, Charles M. (npj Breast Cancer, 2024)
      In this study, we performed genomic analyses of cell cycle and tumor microenvironment changes during and after ribociclib and letrozole or chemotherapy in the CORALLEEN trial. 106 women with untreated ...

    • Cellular Mechanisms that affect Periodontal Destruction induced by Bacteria Infection in Diabetic and Non Diabetic Rats 

      Pacios Pujadó, Sandra (Date of defense: 2014-07-29)
      The aim of this study was to evaluate the histologic and cellular response to A.actinomycetemcomitans (A.a) infection, and how diabetes-enhanced TNF-α production and diabetes-enhanced apoptosis contribute ...

    • Centenari Carmen Laforet 

      Servei de Biblioteca - Universitat Internacional de Catalunya (Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2021-09-06)
      Story conmemorativa amb motiu del centenari del naixement de l'escriptora catalana Carmen Laforet.

    • Centenari Luis García Berlanga 

      Servei de Biblioteca - Universitat Internacional de Catalunya (Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2021-06-14)
      Dissabte es va celebrar el centenari del naixement de Luis García Berlanga, un dels millors directors de la història del cinema espanyol. Són molts els actes que es celebren aquest any per commemorar ...

    • Centenario del nacimiento de Miguel Delibes 

      Servei de Biblioteca - Universitat Internacional de Catalunya (Instagram - Servei de Biblioteca (@bibliouic) - UIC Barcelona, 2020-10-17)
      Hoy 17 de octubre se cumple el Centenario del Nacimiento de Miguel Delibes... Desde la Biblioteca queremos rememorar esta fecha.

    • Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance 

      Contreras, Cristina; González-García, Ismael; Martínez-Sánchez, Noelia; Seoane-Collazo, Patricia; Jacas i Mateu, Jordi; Morgan, Donald A.; Serra, Dolors; Gallego, Rosalía; Gonzalez, Francisco; Casals i Farré, Núria; Nogueiras, Rubén; Rahmouni, Kamal; Diéguez, Carlos; López, Miguel (Cell Reports, 2014-10)
      Hypothalamic endoplasmic reticulum (ER) stress is a key mechanism leading to obesity. Here, we demonstrate that ceramides induce lipotoxicity and hypothalamic ER stress, leading to sympathetic inhibition, ...

    • Central regulation of brown fat thermogenesis in response to saturated or unsaturated long-chain fatty acids 

      Fosch Masllovet, Anna; Rodríguez García, Maria; Miralpeix , Cristina; Zagmutt, Sebastián; Larrañaga Fernandez, Maite; Reguera, Ana Cristina; Garcia-Chica, Jesus; Herrero, Laura; Serra, Dolors; Casals, Nuria; Rodriguez-Rodriguez, Rosalia (International Journal of Molecular Sciences, 2023)
      Sensing of long-chain fatty acids (LCFA) in the hypothalamus modulates energy balance, and its disruption leads to obesity. To date, the effects of saturated or unsaturated LCFA on hypothalamic-brown ...

    • Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast 

      Martínez-Láinez, Joan M.; Moreno, David F.; Parisi, Eva; Clotet Erra, Josep; Aldea Malo, Martí (PLoS Biology, 2018-08-06)
      Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms remain unknown. Using various orthogonal single-cell approaches, we show that cell size increases linearly ...

    • Cerebral oximetry monitoring in extremely preterm infants 

      Hansen, Mathias L.; Pellicer, Adelina; Hyttel-Sørensen, Simon; Ergenekon, Ebru; Szczapa, Tomasz; Hagmann, Cornelia; Naulaers, Gunnar; Mintzer, Jonathan; Fumagalli, Monica; Dimitriou, Gabriel; Dempsey, Eugene; Tkaczyk, Jakub; Cheng, Guoqiang; Fredly, Siv; Heuchan, Anne M.; Pichler, Gerhard; Fuchs, Hans; Nesargi, Saudamini; Hahn, Gitte H.; Piris-Borregas, Salvador; Širc, Jan; Alsina-Casanova, Miguel; Stocker, Martin; Ozkan, Hilal; Sarafidis, Kosmas; Hopper, Andrew O.; Karen, Tanja; Rzepecka-Weglarz, Beata; Oguz, Serife S.; Arruza, Luis; Memisoglu, Asli C.; del Rio Florentino, Ruth; Baserga, Mariana; Maton, Pierre; Truttmann, Anita C.; de las Cuevas, Isabel; Agergaard, Peter; Zafra, Pamela; Bender, Lars; Lauterbach, Ryszard; Lecart, Chantal; de Buyst, Julie; El-Khuffash, Afif; Curley, Anna; Vaccarello, Olalla O.; Miletin, Jan; Papathoma, Evangelia; Vesoulis, Zachary; Vento, Giovanni; Cornette, Luc; Lopez, Laura S.; Yasa, Beril; Klamer, Anja; Agosti, Massimo; Baud, Olivier; Mastretta, Emmanuele; Cetinkaya, Merih; McCall, Karen; Zeng, Shujuan; Hatzidaki, Eleftheria; Bargiel, Agata; Marciniak, Sylwia; Gao, Xiaoyan; Huijia, Lin; Chalak, Lina; Yang, Ling; Rao, Shashidhar A.; Xu, Xin; Gonzalez, Begoña L.; Wilinska, Maria; Yin, Zhaoqing; Sadowska-Krawczenko, Iwona; Serrano-Viñuales, Itziar; Krolak-Olejnik, Barbara; Ybarra, Marta M.; Morales-Betancourt, Catalina; Korček, Peter; Palacio, Marta Teresa; Mosca, Fabio; Hergenhan, Anja; Koksal, Nilgun; Tsoni, Konstantia; Kadri, Munaf M.; Knöpfli, Claudia; Rafinska-Wazny, Elzbieta; Akin, Mustafa S.; Nordvik, Tone; Peng, Zhang; Kersin, Sinem G.; Thewissen, Liesbeth; Alarcon, Ana; Healy, David; Urlesberger, Berndt; Baş, Münevver; Baumgartner, Jana; Skylogianni, Eleni; Karadyova, Veronika; Valverde, Eva; Bergon-Sendin, Elena; Kucera, Jachym; Pisoni, Silvia; Wang, Le; Smits, Anne; Sanchez-Salmador, Rebeca; Rasmussen, Marie I.; Olsen, Markus H.; Jensen, Aksel K.; Gluud, Christian; Jakobsen, Janus C.; Greisen, Gorm (The New England Journal of Medicine, 2023)
      BACKGROUND: The use of cerebral oximetry monitoring in the care of extremely preterm infants is increasing. However, evidence that its use improves clinical outcomes is lacking.: METHODS: In this ...

    • Cerebro, estrés y parentalidad 

      Carballo Márquez, Anna (2017-12-01)

    • Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases 

      Molero‑Luis, Marta; Casas-Alba, Didac; Orellana, Gabriela; Ormazabal, Aida; Sierra, Cristina; Oliva, Clara; Valls, Anna; Velasco, Jesus; Launes, Cristian; Cuadras, Daniel; Pérez‑Dueñas, Belén; Jordan, Iolanda; Cambra, Francisco J.; Ortigoza‑Escobar, Juan D.; Muñoz-Almagro, Carmen; Garcia‑Cazorla, Angels; Armangué, Thais; Artuch, Rafael (Scientific Reports, 2020)
      The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ...

    • La cessió de sòl públic dotacional per a l'obertura de centres docents concertats: una nova manifestació de l'Estat garant 

      Guardia, Juan; Manent Alonso, Luis (Revista Catalana de Dret Públic, 2015-12)
      La última reforma de la Ley Orgánica de Educación acoge una nueva fórmula de apoyo a la enseñanza privada sostenida con fondos públicos en España: la cesión de suelo público dotacional para la construcción ...

    • Challenges for hospital management in supporting nurses to deliver humanized care 

      Martin-Ferreres, Maria Luisa; Wennberg-Capellades, Laia; Rodríguez Higueras, Encarnación; Llauradó Serra, Mireia; De Juan Pardo, Mª Ángeles (Nursing Inquiry, 2021)
      Hospitals are paying increasing attention to the delivery of humanized care. The purpose of this study was to explore from the nursing perspective what hospital managers might do to facilitate this. A ...

    • Challenges in using both eyes of the same patient when evaluating the results after implantation of intrastromal corneal ring segments 

      Lamarca Mateu, José; Salvador-Culla, Borja; Santos, Cristina; I Barraquer, Rafael (Acta Ophthalmologica, 2020)
      Purpose: To assess correlation between results from both eyes of the same patient after implantation of intrastromal corneal ring segments (ICRS) and define whether they can be used together in clinical ...

    • Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project 

      Bennett, Julia C.; Hetrich, Marissa K.; Garcia Quesada, Maria; Sinkevitch, Jenna N.; Deloria Knoll, Maria; Feikin, Daniel R.; Zeger, Scott L.; Kagucia, Eunice W.; Cohen, Adam L.; Ampofo, Krow; Brandileone, Maria-Cristina; Bruden, Dana; Camilli, Romina; Castilla, Jesús; Chan, Guanhao; Cook, Heather; Cornick, Jennifer E.; Dagan, Ron; Dalby, Tine; Danis, Kostas; De Miguel, Sara; De Wals, Philippe; Desmet, Stefanie; Georgakopoulou, Theano; Gilkison, Charlotte; Grgic-Vitek, Marta; Hammitt, Laura L.; Hilty, Markus; Ho, Pak-Leung; Jayasinghe, Sanjay; Kellner, James D.; Kleynhans, Jackie; Knol, Mirjam J.; Kozakova, Jana; Kristinsson, Karl G.; Ladhani, Shamez N.; MacDonald, Laura; Mackenzie, Grant A.; Mad’arová, Lucia; McGeer, Allison; Mereckiene, Jolita; Morfeldt, Eva; Mungun, Tuya; Muñoz-Almagro, Carmen; Nuort, J. Pekka; Paragi, Metka; Pilishvili, Tamara; Puentes, Rodrigo; Saha, Samir K.; Sahu Khan, Aalisha; Savrasova, Larisa; Scott, J. Anthony; Skoczynska, Anna; Suga, Shigeru; Van Der Linden, Mark; Verani, Jennifer R.; Von Gottberg, Anne; Winje, Brita A.; Yildirim, Inci; Zerouali, Khalid; Hayford, Kyla; PSERENADE Team (Microorganisms, 2021)
      Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. ...

    • Changes in invasive pneumococcal disease in the paediatric population in the second COVID-19 pandemic year 

      Izquierdo, Conchita; Ciruela, Pilar; Soldevila, Núria; Garcia-Garcia, Juan-Jose; Gonzalez-Peris, Sebastia; Díaz-Conradi, Alvaro; Viñado, Belen; De Sevilla, Mariona F.; Moraga-Llop, Fernando; Muñoz-Almagro, Carmen; Domínguez, Angela; Barcino Working Group (Vaccines, 2023)
      Incidence of invasive pneumococcal disease (IPD) decreased worldwide in 2020, coinciding with the implementation of measures to reduce COVID-19 transmission. We evaluated the impact of the COVID-19 ...