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Listando por materia "Polimorfismos"

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    • Dihydropyrimidine dehydrogenases and cytidine-deaminase gene polymorphisms as outcome predictors in resected gastric cancer patients treated with fluoropyrimidine adjuvant chemotherapy 

      GRAU, JUAN-JOSE; Caballero Borrego, Miguel; MONZO, MARIANO; Munoz, Patricia; Domingo-Domenech, Josep; Navarro, Alfons; conill, carlos; Campayo, Marc; Bombí, Jose A. (Journal of Surgical Oncology, 2008-08-01)
      Background and Objectives: Single nucleotide polymorphisms of dihydropyrimidine dehydrogenases gene (DPYD) induces dihydropyrimidinedehydrogenase enzyme (DPD) deficiency resulting in increased activity ...
    • Gene Single Nucleotide PolymorphismAccumulation Improves Survival in Advanced Head and Neck Cancer PatientsTreated With Weekly Paclitaxel 

      GRAU, JUAN-JOSE; Caballero Borrego, Miguel; Campayo, Marc; Sonia, Jansa; Vargas, Mauricio; Alos, Llucia; MONZO, MARIANO (The Laryngoscope, 2009-08)
      Objectives/Hypothesis: Single nucleotide polymorphisms (SNPs) of certain genes involved in drug metabolism correlate with survival. Methods: We evaluated the presence of SNPs in six genes (CYP2C8, ...
    • Single Nucleotide Polymorphisms in Tobacco Metabolism and DNA Repair Genes and Prognosis in Resected Non-Small-Cell Lung Cancer 

      Campayo, Marc; Vinolas Segarra, Nuria; Navarro, Alfons; carcereny, Enric; Casas, Francesc; Gel Moreno, Bernat; Díaz Sánchez, Tània; Gimferrer Garolera, Josep M; Marrades Sicart, Ramon; Ramírez, Jose; MONZO, MARIANO (Journal of Surgical Research, 2011-05-01)
      Background If tobacco-related carcinogens are not inactivated or extruded from the cell, they can damage the DNA. Single nucleotide polymorphisms (SNPs) in genes involved in tobacco metabolism, DNA ...
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