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A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Cell Reports, 2012-10-25)Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ... -
ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer
(Oncotarget, 2018-03-30)Endometrial cancer (EC) is the sixth deadliest cancer in women. The depth of myometrial invasion is one of the most important prognostic factors, being directly associated with tumor recurrence and ... -
Complete loss of EPCAM immunoexpression identifies EPCAM deletion carriers in MSH2-negative colorectal neoplasia
(MDPI, 2020)The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the ... -
Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose or oral iron as preoperative treatment in patients with colon cancer and iron deficiency anaemia
(Technology and Health Care, 2016)Background: Ferric Carboxymaltose (FCM), Iron Sucrose (IS) and Oral Iron (OI) are alternative treatments for preoper-ative anaemia. Objective: To compare the cost implications, using a cost-minimization ... -
Sarcoma de Kaposi de diagnóstico intraoral
(Revista Española de Cirugía Oral y Maxilofacial, 2017) -
The impact of KRAS mutations on VEGF-A production and tumour vascular network
(BMC Cancer, 2013-03-18)Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ...