Visualitzant per matèria "Polymorphisms"
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Dihydropyrimidine dehydrogenases and cytidine-deaminase gene polymorphisms as outcome predictors in resected gastric cancer patients treated with fluoropyrimidine adjuvant chemotherapy
(Journal of Surgical Oncology, 2008-08-01)Background and Objectives: Single nucleotide polymorphisms of dihydropyrimidine dehydrogenases gene (DPYD) induces dihydropyrimidinedehydrogenase enzyme (DPD) deficiency resulting in increased activity ... -
Gene Single Nucleotide PolymorphismAccumulation Improves Survival in Advanced Head and Neck Cancer PatientsTreated With Weekly Paclitaxel
(The Laryngoscope, 2009-08)Objectives/Hypothesis: Single nucleotide polymorphisms (SNPs) of certain genes involved in drug metabolism correlate with survival. Methods: We evaluated the presence of SNPs in six genes (CYP2C8, ... -
Single Nucleotide Polymorphisms in Tobacco Metabolism and DNA Repair Genes and Prognosis in Resected Non-Small-Cell Lung Cancer
(Journal of Surgical Research, 2011-05-01)Background If tobacco-related carcinogens are not inactivated or extruded from the cell, they can damage the DNA. Single nucleotide polymorphisms (SNPs) in genes involved in tobacco metabolism, DNA ...