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Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation

Le Dily, François; Bau, Davide; Pohl, Andy; Vicent, Guillermo P.; Serra, Francois; Soronellas, Daniel; Castellano, Giancarlo; Wright, Roni; Ballare, Cecilia; Filion, Guillaume; Marti-Renom, Marc A.; Beato, Miguel (Genes & Development, 2014)

The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ...