• Development of a serum-free medium to aid large-scale production of mycoplasma-based therapies 

      Burgos, Raul; Garcia-Ramallo, Eva; Shaw, Daniel; Lluch-Senar, Maria; Serrano, Luis (Microbiology Spectrum, 2023)
      To assist in the advancement of the large-scale production of safe Mycoplasma vaccines and other Mycoplasma-based therapies, we developed a culture medium free of animal serum and other animal components ...
    • Engineering a genome reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo 

      Garrido, Victoria; Piñero Lambea, Carlos; Rodriguez Arce, Irene; Paetzold, Bernhard; Ferrar, Tony; Weber, Marc; Garcia Ramallo, Eva; Gallo López, Carolina; Collantes, María; Penuelas, Ivan; Serrano, Luis; Grillo, Maria-Jesus; Lluch, Maria (Molecular Systems Biology, 2021)
      Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated ...