Visualitzant per matèria "Genomas"
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Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
(PLoS Biology, 2018-08-06)Cell size scales with ploidy in a great range of eukaryotes, but the underlying mechanisms remain unknown. Using various orthogonal single-cell approaches, we show that cell size increases linearly ... -
Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis
(Neurology: Neuroimmunology & Neuroinflammation, 2020)Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ... -
Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival
(Journal of Biological Chemistry, 2012-03-30)NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ... -
The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
(Genome Biology, 2010-06-23)Background: The G1-to-S transition of the cell cycle in the yeast Saccharomyces cerevisiae involves an extensive transcriptional program driven by transcription factors SBF (Swi4-Swi6) and MBF (Mbp1-Swi6). ... -
A two-base deletion in exon 6 of the 3-hydroxy-3- methylglutaryl coenzyme A lyase (HL) gene producing the skipping of exons 5 and 6 determines 3- hydroxy-3-methylglutaric aciduria
(Journal of Lipid Research, 1997)A novel two-base deletion in the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene was found in a Spanish patient with homozygous 3-hydroxy-3-methylglutaric aciduria. Amplification by RT-PCR of the ...