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Visualitzant per matèria "Drug resistance"

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    • Antibacterial approaches in tissue engineering using metal ions and nanoparticles: from mechanisms to applications 

      Godoy Gallardo, Maria; Eckhard, Ulrich; Delgado, Luis M.; de Roo Puente, Yolanda J.D.; Hoyos Nogués, Mireia; Gil Mur, Francisco Javier; Pérez Antoñanzas, Roman (Bioactive Materials, 2021-12)
      Bacterial infection of implanted scaffolds may have fatal consequences and, in combination with the emergence of multidrug bacterial resistance, the development of advanced antibacterial biomaterials ...
    • Detection and expression analysis of tet(B) in streptococcus oralis 

      Arredondo, Alexandre; Àlvarez, Gerard; Nart Molina, José; Mor Reinoso, Carolina; Blanc, Vanessa; León, Rubén (Journal of Oral Microbiology, 2019)
      Tetracycline resistance can be achieved through tet genes, which code for efflux pumps, ribosomal protection proteins and inactivation enzymes. Some of these genes have only been described in either ...
    • Reducing the duration of antibiotic therapy in surgical patients through a specific nationwide antimicrobial stewardship program. A prospective, interventional cohort study 

      Batlle, Maria; Badia, Josep M.; Hernández, Sergi; Grau, Santiago; Padulles, Ariadna; Boix-Palop, Lucía; Giménez-Pérez, Montserrat; Ferrer, Ricard; Calbo, Esther; Limón, Enric; Pujol, Miquel; Horcajada, Juan P. (International Journal of Antimicrobial Agents, 2023)
      Background: Guidelines recommend 5–7 days of antibiotic treatment in patients with surgical infection and adequate source control. This nationwide stewardship intervention aimed to reduce the duration ...
    • Surgeon-led 7-VINCut antibiotic stewardship intervention decreases duration of treatment and carbapenem use in a general surgery service 

      Badia, Josep M; Batlle, Maria; Juvany, Montserrat; Ruiz-de León, Patricia; Sagalés, Maria; Pulido, M. Angeles; Molist, Gemma; Cuquet, Jordi (Antibiotics, 2021)
      Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary ...
    • Targeting the Src N-terminal regulatory element in cancer 

      Mezquita, Betlem; Reyes-Farias, Marjorie; Pons, Miquel (Oncotarget, 2023)
      The signaling pathways displayed by cancer cells are often composed by the same components than the physiological ones, yet the overall result is a pathological deregulation. The non-receptor protein ...
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