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CPT1C deficiency in SF1 neurons impairs early metabolic adaptation to dietary fats, leading to obesity
(Molecular Metabolism, 2025)Objectives: SF1 neurons of the ventromedial hypothalamus (VMH) play a pivotal role in regulating body weight and adiposity, particularly in response to a high-fat diet (HFD), as well as in the recovery ... -
Identification of the ghrelin and cannabinoid CB2 receptor heteromer functionality and marked upregulation in striatal neurons from offspring of mice under a high-fat diet
(International Journal of Molecular Sciences, 2021)Cannabinoids have been reported as orexigenic, i.e., as promoting food intake that, among others, is controlled by the so-called “hunger” hormone, ghrelin. The aim of this paper was to look for functional ...