Visualitzant per matèria "CPT1A"
Ara mostrant els elements 1-3 de 3
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CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
(Biology of Sex Differences, 2023)Background: Fatty acid metabolism in the hypothalamus has an important role in food intake, but its specific role in AgRP neurons is poorly understood. Here, we examined whether carnitinea palmitoyltransferase ... -
Development of C75-CoA loaded polymeric micelles targeting brain CPT1A: A novel nanomedicine-based approach to fight obesity and cancer
(Data de defensa: 2024-02-14)Brain lipid metabolism has a key role in many physiological processes, and its malfunction is associated with a plethora of diseases, such as obesity and glioblastoma multiforme (GBM). Carnitine palmitoyl ... -
Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: a promising strategy to regulate energy balance
(Journal of Neuroendocrinology, 2023)Tackling the growing incidence and prevalence of obesity urgently requires uncovering new molecular pathways with therapeutic potential. The brain, and in particular the hypothalamus, is a major integrator ...