Recommendations for diagnosis, treatment, and prevention of iron deficiency and iron deficiency anemia
Autor/a
Iolascon, Achille
Andolfo, Immacolata
Russo, Roberta
Busti, Fabiana
Swinkels, Dorine
Aguilar Martinez, Patricia
Bou‐Fakhredin, Rayan
Muckenthaler, Martina U.
Unal, Sule
Porto, Graça
Ganz, Tomas
Kattamis, Antonis
De Franceschi, Lucia
Cappellini, Maria Domenica
Munro, Malcolm G.
Taher, Ali
Fecha de publicación
2024ISSN
2572-9241
Resumen
Iron is an essential nutrient and a constituent of ferroproteins and enzymes crucial for human life. Generally, nonmenstruating individuals preserve iron very efficiently, losing less than 0.1% of their body iron content each day, an amount that is replaced through dietary iron absorption. Most of the iron is in the hemoglobin (Hb) of red blood cells (RBCs); thus, blood loss is the most common cause of acute iron depletion and anemia worldwide, and reduced hemoglobin synthesis and anemia are the most common consequences of low plasma iron concentrations. The term iron deficiency (ID) refers to the reduction of total body iron stores due to impaired nutrition, reduced absorption secondary to gastrointestinal conditions, increased blood loss, and increased needs as in pregnancy. Iron deficiency anemia (IDA) is defined as low Hb or hematocrit associated with microcytic and hypochromic erythrocytes and low RBC count due to iron deficiency. IDA most commonly affects women of reproductive age, the developing fetus, children, patients with chronic and inflammatory diseases, and the elderly. IDA is the most frequent hematological disorder in children, with an incidence in industrialized countries of 20.1% between 0 and 4 years of age and 5.9% between 5 and 14 years (39% and 48.1% in developing countries). The diagnosis, management, and treatment of patients with ID and IDA change depending on age and gender and during pregnancy. We herein summarize what is known about the diagnosis, treatment, and prevention of ID and IDA and formulate a specific set of recommendations on this topic.
Tipo de documento
Artículo
Versión del documento
Versión publicada
Lengua
English
Materias (CDU)
61 - Medicina
Palabras clave
Anemia
Anèmia
Anemia
Páginas
16
Publicado por
Wiley
Colección
8; 7
Publicado en
Hemasphere
Citación
Iolascon, Achill; Andolfo, Immacolata; Russo, Roberta [et al.]. Recommendations for diagnosis, treatment, and prevention of iron deficiency and iron deficiency anemia. Hemasphere, 2024, 8(7), e108. Disponible en: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11247274/>. Fecha de acceso: 3 sep. 2024. DOI: 10.1002/hem3.108
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Derechos
© 2024 The Author(s). HemaSphere published by John Wiley & Sons Ltd on behalf of European Hematology Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
Excepto si se señala otra cosa, la licencia del ítem se describe como https://creativecommons.org/licenses/by-nc-nd/4.0/