dc.contributor.author | Mossa, Alessandro | |
dc.contributor.author | de Lorenzo, Sara | |
dc.contributor.author | Huguet Casades, Josep Maria | |
dc.contributor.author | Ritort, Felix | |
dc.date.accessioned | 2024-03-18T14:04:14Z | |
dc.date.available | 2024-03-18T14:04:14Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Mossa, Alessandro; de Lorenzo, Sara; Huguet Casades, Josep Maria [et al.]. Measurement of work in single-molecule pulling experiments. The Journal of Chemical Physics, 2009, 130, 234116. Disponible en: <https://pubs.aip.org/aip/jcp/article-abstract/130/23/234116/924758/Measurement-of-work-in-single-molecule-pulling?redirectedFrom=fulltext>. Fecha de acceso: 18 mar. 2024. DOI: 10.1063/1.3155084 | ca |
dc.identifier.issn | 0021-9606 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/4166 | |
dc.description.abstract | A main goal of single-molecule experiments is to evaluate equilibrium free energy differences by applying fluctuation relations to repeated work measurements along irreversible processes. We quantify the error that is made in a free energy estimate by means of the Jarzynski equality when the accumulated work expended on the whole system (including the instrument) is erroneously replaced by the work transferred to the subsystem consisting of the sole molecular construct. We find that the error may be as large as 100%, depending on the number of experiments and on the bandwidth of the data acquisition apparatus. Our theoretical estimate is validated by numerical simulations and pulling experiments on DNA hairpins using optical tweezers. | ca |
dc.format.extent | Desconocido | ca |
dc.language.iso | eng | ca |
dc.publisher | AIP Publishing | ca |
dc.relation.ispartof | The Journal of Chemical Physics | ca |
dc.relation.ispartofseries | 130 | |
dc.rights | © Copyright 2024 AIP Publishing LLC. | ca |
dc.subject.other | Energia lliure | ca |
dc.subject.other | Termodinàmica sense equilibri | ca |
dc.subject.other | Procés irreversible | ca |
dc.subject.other | Propietats termodinàmiques | ca |
dc.subject.other | Adquisició de dades | ca |
dc.subject.other | Simulació per ordinador | ca |
dc.subject.other | Pinces òptiques | ca |
dc.subject.other | Processos gaussians | ca |
dc.subject.other | Teoremes de mecànica estadística | ca |
dc.subject.other | Equació de mecànica estadística | ca |
dc.subject.other | Energía libre | ca |
dc.subject.other | Termodinámica de desequilibrio | ca |
dc.subject.other | Proceso irreversible | ca |
dc.subject.other | Propiedades termodinámicas | ca |
dc.subject.other | Adquisición de datos | ca |
dc.subject.other | Simulación por ordenador | ca |
dc.subject.other | Pinzas ópticas | ca |
dc.subject.other | Procesos gaussianos | ca |
dc.subject.other | Teoremas de la mecánica estadística | ca |
dc.subject.other | Ecuación de la mecánica estadística | ca |
dc.subject.other | Free energy | ca |
dc.subject.other | Nonequilibrium thermodynamics | ca |
dc.subject.other | Irreversible process | ca |
dc.subject.other | Thermodynamic properties | ca |
dc.subject.other | Data acquisition | ca |
dc.subject.other | Computer simulation | ca |
dc.subject.other | Optical tweezers | ca |
dc.subject.other | Gaussian processes | ca |
dc.subject.other | Statistical mechanics theorems | ca |
dc.subject.other | Statistical mechanics equation | ca |
dc.title | Measurement of work in single-molecule pulling experiments | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.subject.udc | 57 | ca |
dc.identifier.doi | https://dx.doi.org/10.1063/1.3155084 | ca |